Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3064
Gene Symbol: HTT
HTT
huntingtin 0.548 0.654 1.00
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 1.000 limited 0.987 15 0 1993 2020
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.300 None 0.966 2 0 2006 2019
Entrez Id: 84152
Gene Symbol: PPP1R1B
PPP1R1B
protein phosphatase 1 regulatory inhibitor subunit 1B 0.617 0.500 0.24
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.300 None 1.000 1 0 2004 2019
Entrez Id: 1270
Gene Symbol: CNTF
CNTF
ciliary neurotrophic factor 0.561 0.615 2.3E-05
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.300 None 0.846 1 0 1997 2008
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.300 None 1.000 1 0 2010 2019
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
cAMP responsive element binding protein 1 0.463 0.885 1.00
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.270 None 1.000 1 0 2006 2018
Entrez Id: 23390
Gene Symbol: ZDHHC17
ZDHHC17
zinc finger DHHC-type palmitoyltransferase 17 0.890 0.269 1.00
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.270 None 0.875 1 0 2002 2017
Entrez Id: 4852
Gene Symbol: NPY
NPY
neuropeptide Y 0.447 0.846 0.14
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.250 None 1.000 1 0 1991 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.250 None 1.000 1 0 2004 2019
Entrez Id: 3708
Gene Symbol: ITPR1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1 0.534 0.846 1.00
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.240 None 1.000 1 0 1998 2014
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.230 None 1.000 1 0 1998 2017
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
peroxisome proliferator activated receptor delta 0.513 0.846 0.99
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.230 None 1.000 0 0 2016 2020
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
cannabinoid receptor 2 0.509 0.846 6.5E-06
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.220 None 1.000 1 0 2009 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.220 None 1.000 1 0 1999 2015
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13
zinc finger DHHC-type palmitoyltransferase 13 0.729 0.346 1.2E-19
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.220 None 1.000 1 0 2012 2015
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
dopamine receptor D1 0.529 0.808 0.96
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.210 None 1.000 1 0 1994 2008
Entrez Id: 581
Gene Symbol: BAX
BAX
BCL2 associated X, apoptosis regulator 0.417 0.885 0.32
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 2 0 2001 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 2011 2011
Entrez Id: 18
Gene Symbol: ABAT
ABAT
4-aminobutyrate aminotransferase 0.628 0.538 6.3E-03
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 1977 1977
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 23475
Gene Symbol: QPRT
QPRT
quinolinate phosphoribosyltransferase 0.736 0.346 4.7E-03
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 1989 1989
Entrez Id: 4537
Gene Symbol: ND3
ND3
NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4155
Gene Symbol: MBP
MBP
myelin basic protein 0.510 0.885 0.28
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 2012 2012
Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
dual specificity phosphatase 1 0.491 0.808 1.0E-02
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 2013 2013
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
E2F transcription factor 1 0.441 0.846 0.99
CUI: C0020179
Disease: Huntington Disease
Huntington Disease
disease 0.200 None 1.000 1 0 2008 2008