×
Entrez Id:
4176
Gene Symbol:
MCM7
MCM7
Hepatoblastoma
0.200
SusceptibilityMutation
RGD
A genetic variant in the promoter region of miR-106b-25 cluster predict clinical outcome of HBV-related hepatocellular carcinoma in Chinese.
24416400
2014
×
Entrez Id:
407014
Gene Symbol:
MIR25
MIR25
Hepatoblastoma
0.200
ModifyingMutation
RGD
A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer.
30191950
2019
×
Entrez Id:
406953
Gene Symbol:
MIR18A
MIR18A
Hepatoblastoma
0.200
ModifyingMutation
RGD
A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer.
30191950
2019
×
Entrez Id:
6722
Gene Symbol:
SRF
SRF
Hepatoblastoma
0.200
Biomarker
RGD
Activation of serum response factor in the liver of Long-Evans Cinnamon (LEC) rat.
9570363
1997
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Hepatoblastoma
0.210
Biomarker
RGD
Activation of the c-Ki-ras oncogene in aflatoxin B1-induced hepatocellular carcinoma and adenoma in the rat: detection by denaturing gradient gel electrophoresis.
8446626
1993
×
Entrez Id:
2
Gene Symbol:
A2M
A2M
Hepatoblastoma
0.200
Biomarker
RGD
alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers.
15509519
2004
×
Entrez Id:
2272
Gene Symbol:
FHIT
FHIT
Hepatoblastoma
0.200
Biomarker
RGD
Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats.
12112319
2002
×
Entrez Id:
4609
Gene Symbol:
MYC
MYC
Hepatoblastoma
0.220
Therapeutic
RGD
Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.
22129741
2011
×
Entrez Id:
5111
Gene Symbol:
PCNA
PCNA
Hepatoblastoma
0.510
Therapeutic
RGD
Boron inhibits the proliferating cell nuclear antigen index, molybdenum containing proteins and ameliorates oxidative stress in hepatocellular carcinoma.
23219601
2013
×
Entrez Id:
825
Gene Symbol:
CAPN3
CAPN3
Hepatoblastoma
0.200
Biomarker
RGD
Calpain-3 gene expression is decreased during experimental cancer cachexia.
10806331
2000
×
Entrez Id:
898
Gene Symbol:
CCNE1
CCNE1
Hepatoblastoma
0.200
Biomarker
RGD
Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism.
17196522
2007
×
Entrez Id:
3481
Gene Symbol:
IGF2
IGF2
Hepatoblastoma
0.700
Biomarker
RGD
Changes in the antioxidant defense and hepatic drug metabolizing enzyme and isoenzyme levels, 8-hydroxydeoxyguanosine formation and expressions of c-raf.1 and insulin-like growth factor II genes during the stages of development of hepatocellular carcinoma in rats.
17554210
2007
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Hepatoblastoma
0.210
Therapeutic
RGD
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model.
29133031
2018
×
Entrez Id:
842
Gene Symbol:
CASP9
CASP9
Hepatoblastoma
0.200
Therapeutic
RGD
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model.
29133031
2018
×
Entrez Id:
841
Gene Symbol:
CASP8
CASP8
Hepatoblastoma
0.200
Therapeutic
RGD
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model.
29133031
2018
×
Entrez Id:
80781
Gene Symbol:
COL18A1
COL18A1
Hepatoblastoma
0.200
ModifyingMutation
RGD
Combined endostatin/sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC.
15739185
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
Hepatoblastoma
0.210
Biomarker
RGD
CpG site hypermethylation of E-cadherin and Connexin26 genes in hepatocellular carcinomas induced by a choline-deficient L-Amino Acid-defined diet in rats.
17295234
2007
×
Entrez Id:
2706
Gene Symbol:
GJB2
GJB2
Hepatoblastoma
0.200
Biomarker
RGD
CpG site hypermethylation of E-cadherin and Connexin26 genes in hepatocellular carcinomas induced by a choline-deficient L-Amino Acid-defined diet in rats.
17295234
2007
×
Entrez Id:
406900
Gene Symbol:
MIR106B
MIR106B
Hepatoblastoma
0.200
Biomarker
RGD
Crosstalk between liver-related microRNAs and Wnt/β-catenin pathway in hepatocellular carcinoma patients.
28958640
2017
×
Entrez Id:
208
Gene Symbol:
AKT2
AKT2
Hepatoblastoma
0.200
Biomarker
RGD
Crosstalk between PTEN/Akt2 and TGFbeta signaling involving EGF receptor down-regulation during the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model.
19309364
2009
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Hepatoblastoma
0.230
Biomarker
RGD
De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats.
12359353
2002
×
Entrez Id:
8714
Gene Symbol:
ABCC3
ABCC3
Hepatoblastoma
0.200
Biomarker
RGD
Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development.
25842354
2015
×
Entrez Id:
7409
Gene Symbol:
VAV1
VAV1
Hepatoblastoma
0.200
Biomarker
RGD
DNA methylation and oncogene expression in methapyrilene-induced rat liver tumors and in treated hepatocytes in culture.
2064726
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Hepatoblastoma
0.400
Biomarker
RGD
Effect of human umbilical cord blood derived CD34+ hematopoietic stem cell on the expression of Wnt4 and P53 genes in a rat model of hepatocellular carcinoma.
29429512
2018
×
Entrez Id:
1514
Gene Symbol:
CTSL
CTSL
Hepatoblastoma
0.200
Biomarker
RGD
Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats.
15641152
2005