Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers. 15509519

2004

Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.210 Biomarker RGD Hypercholesterolemia in rats with hepatomas: increased oxysterols accelerate efflux but do not inhibit biosynthesis of cholesterol. 16941710

2006

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker RGD Verapamil and rifampin effect on p-glycoprotein expression in hepatocellular carcinoma. 25625052

2014

Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.240 Biomarker RGD Differential Expression of Ion Channels and Transporters During Hepatocellular Carcinoma Development. 25842354

2015

Entrez Id: 134526
Gene Symbol: ACOT12
ACOT12
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.210 Biomarker RGD The biphasic change of cytosolic acetyl-CoA hydrolase in rat liver during 3'-methyl-4-dimethylaminoazobenzene hepatocarcinogenesis. 2566591

1989

Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD Gel-based proteomics of liver cancer progression in rat. 21683810

2011

Entrez Id: 208
Gene Symbol: AKT2
AKT2
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.210 Biomarker RGD Crosstalk between PTEN/Akt2 and TGFbeta signaling involving EGF receptor down-regulation during the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model. 19309364

2009

Entrez Id: 230
Gene Symbol: ALDOC
ALDOC
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD Molecular cloning and expression of rat aldolase C messenger RNA during development and hepatocarcinogenesis. 3830170

1987

Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.240 Biomarker RGD The apparent Km values for adenine of liver and hepatoma adenine phosphoribosyltransferase were 0.6 to 0.9 microM, respectively. 6327016

1984

Entrez Id: 440
Gene Symbol: ASNS
ASNS
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.500 Biomarker RGD L-Asparagine synthetase in serum as a marker for neoplasia. 10081

1976

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.210 Biomarker RGD Elevated expression of complement C3 protein in chemically induced hepatotumorogenesis in Wistar rats: a correlative proteomics and histopathological study. 23245919

2013

Entrez Id: 790
Gene Symbol: CAD
CAD
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.220 Biomarker RGD Southern and DNA dot blots indicated amplification of CAD hepatoma 3924A synthase II gene product. 2888462

1987

Entrez Id: 790
Gene Symbol: CAD
CAD
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.220 Biomarker RGD Increased incidence of CAD gene amplification in tumorigenic rat lines as an indicator of genomic instability of neoplastic cells. 2914957

1989

Entrez Id: 23705
Gene Symbol: CADM1
CADM1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD Expression and DNA methylation patterns of Tslc1 and Dal-1 genes in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. 17428255

2007

Entrez Id: 825
Gene Symbol: CAPN3
CAPN3
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD Calpain-3 gene expression is decreased during experimental cancer cachexia. 10806331

2000

Entrez Id: 10498
Gene Symbol: CARM1
CARM1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD Elevated expression of coactivator-associated arginine methyltransferase 1 is associated with early hepatocarcinogenesis. 23912631

2013

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.260 Therapeutic RGD Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. 29133031

2018

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Therapeutic RGD Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. 29133031

2018

Entrez Id: 842
Gene Symbol: CASP9
CASP9
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Therapeutic RGD Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. 29133031

2018

Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.220 Biomarker RGD Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. 17196522

2007

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.200 Biomarker RGD CpG site hypermethylation of E-cadherin and Connexin26 genes in hepatocellular carcinomas induced by a choline-deficient L-Amino Acid-defined diet in rats. 17295234

2007

Entrez Id: 983
Gene Symbol: CDK1
CDK1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.240 Biomarker RGD Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC. 19136513

2009

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.690 Biomarker RGD Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular carcinoma. 11301474

2001

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.690 Biomarker RGD Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer. 16317707

2005

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.690 Biomarker RGD De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats. 12359353

2002