Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4191
Gene Symbol: MDH2
MDH2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Effects of ischemia and pharmacological treatment on subcellular fractions from neonatal rat brain. 6282622

1982

Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. 1830327

1991

Entrez Id: 7832
Gene Symbol: BTG2
BTG2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Immediate early gene induction after neonatal hypoxia-ischemia. 7684483

1993

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Endothelin levels increase in rat focal and global ischemia. 8113329

1994

Entrez Id: 3313
Gene Symbol: HSPA9
HSPA9
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD In situ analysis of normal brain reveals an unusual distribution, with very high expression in neurons of the basal forebrain, reticular and subthalamic nuclei, globus pallidus, amygdala and elsewhere. grp75-mRNA is upregulated following focal brain ischemia in a distinctive fashion. 7629893

1995

Entrez Id: 1439
Gene Symbol: CSF2RB
CSF2RB
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cloning of rat interleukin-3 receptor beta-subunit from cultured microglia and its mRNA expression in vivo. 7643220

1995

Entrez Id: 2746
Gene Symbol: GLUD1
GLUD1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Accumulation of ammonia and changes in the activity of some ammonia metabolizing enzymes during brain ischemia/reperfusion injury in rats. 7808037

1995

Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Focal cerebral ischemia induces CRH mRNA in rat cerebral cortex and amygdala. 8541482

1995

Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons. 9030714

1997

Entrez Id: 4671
Gene Symbol: NAIP
NAIP
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. 9288726

1997

Entrez Id: 1234
Gene Symbol: CCR5
CCR5
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Cloning of rat HIV-1-chemokine coreceptor CKR5 from microglia and upregulation of its mRNA in ischemic and endotoxinemic rat brain. 9670989

1998

Entrez Id: 6364
Gene Symbol: CCL20
CCL20
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation. 9916893

1998

Entrez Id: 2100
Gene Symbol: ESR2
ESR2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors. 10414967

1999

Entrez Id: 2674
Gene Symbol: GFRA1
GFRA1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Induction of glial cell line-derived neurotrophic factor receptor proteins in cerebral cortex and striatum after permanent middle cerebral artery occlusion in rats. 10407114

1999

Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Induction of glial cell line-derived neurotrophic factor receptor proteins in cerebral cortex and striatum after permanent middle cerebral artery occlusion in rats. 10407114

1999

Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells. 10964954

2000

Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Galectin-3 is upregulated in microglial cells in response to ischemic brain lesions, but not to facial nerve axotomy. 10931529

2000

Entrez Id: 1848
Gene Symbol: DUSP6
DUSP6
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. 10908038

2000

Entrez Id: 654
Gene Symbol: BMP6
BMP6
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Expression of bone morphogenetic protein-6 and transforming growth factor-beta1 in the rat brain after a mild and reversible ischemic damage. 11245809

2001

Entrez Id: 1813
Gene Symbol: DRD2
DRD2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD mRNA D(2) dopaminergic receptor expression after hypoxia-ischemia in rat immature brain. 11474153

2001

Entrez Id: 839
Gene Symbol: CASP6
CASP6
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Caspase mRNA expression in a rat model of focal cerebral ischemia. 11311984

2001

Entrez Id: 2638
Gene Symbol: GC
GC
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Acute-phase proteins before cerebral ischemia in stroke-prone rats: identification by proteomics. 11239198

2001

Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.510 Biomarker RGD In this study, the authors analyzed the expression pattern of interleukin-18, -1beta, and caspase-1 in focal brain ischemia induced in rats either by permanent middle cerebral artery occlusion or by photothrombosis of cortical microvessels. 11807395

2002

Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.220 Biomarker RGD Altered gene expression of Na+/Ca2+ exchanger isoforms NCX1, NCX2 and NCX3 in chronic ischemic rat brain. 12377375

2002

Entrez Id: 5566
Gene Symbol: PRKACA
PRKACA
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats. 12150772

2002