Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The quantification of ADAMTS expression in an animal model of cerebral ischemia using real-time PCR. 17073862

2007

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.230 Biomarker RGD RAGE is expressed in pyramidal cells of the hippocampus following moderate hypoxic-ischemic brain injury in rats. 12618340

2003

Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.220 Biomarker RGD Time dependent changes of striatal interneurons after focal cerebral ischemia in rats. 18301954

2008

Entrez Id: 8165
Gene Symbol: AKAP1
AKAP1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia. 18323779

2008

Entrez Id: 9590
Gene Symbol: AKAP12
AKAP12
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: correlations with angiogenesis and cerebral edema. 21334414

2011

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation. 21596097

2011

Entrez Id: 246
Gene Symbol: ALOX15
ALOX15
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability. 20167207

2010

Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats. 20204486

2010

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD The effect of recombinant human erythropoietin on neurovasculature repair after focal ischemic stroke in neonatal rats. 17494864

2007

Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain. 1830327

1991

Entrez Id: 317
Gene Symbol: APAF1
APAF1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Greater stress protein expression enhanced by combined prostaglandin A1 and lithium in a rat model of focal ischemia. 17640469

2007

Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Loss of Ref-1 protein expression precedes DNA fragmentation in apoptotic neurons. 9030714

1997

Entrez Id: 360
Gene Symbol: AQP3
AQP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Our findings indicated that dynamic changes of AQP3, -4, -5 and -8 expression could contribute to the development of cerebral edema after brain ischemia. 19616516

2009

Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. 19616516

2009

Entrez Id: 362
Gene Symbol: AQP5
AQP5
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. 19616516

2009

Entrez Id: 343
Gene Symbol: AQP8
AQP8
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. 19616516

2009

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Melatonin attenuates the focal cerebral ischemic injury by inhibiting the dissociation of pBad from 14-3-3. 18078455

2008

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Therapeutic RGD Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus. 15585409

2005

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD A high soy diet reduces programmed cell death and enhances bcl-xL expression in experimental stroke. 17706879

2007

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats. 19574998

2009

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.210 Biomarker RGD Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death. 17936001

2008

Entrez Id: 654
Gene Symbol: BMP6
BMP6
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Expression of bone morphogenetic protein-6 and transforming growth factor-beta1 in the rat brain after a mild and reversible ischemic damage. 11245809

2001

Entrez Id: 7832
Gene Symbol: BTG2
BTG2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Immediate early gene induction after neonatal hypoxia-ischemia. 7684483

1993