| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.700 | None | 0.983 | 2577 | 53 | 1997 | 2020 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.500 | None | 0.983 | 987 | 35 | 2002 | 2020 | ||||||||
|
PTEN induced kinase 1 | 0.516 | 0.769 | 1.9E-10 |
|
disease | 0.600 | None | 0.987 | 376 | 12 | 2002 | 2020 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.600 | None | 0.974 | 304 | 20 | 1998 | 2020 | ||||||||
|
glucosylceramidase beta | 0.500 | 0.808 | 1.4E-06 |
|
disease | 0.500 | None | 0.989 | 264 | 15 | 2004 | 2020 | ||||||||
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.935 | 185 | 7 | 1994 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.500 | None | 0.972 | 142 | 40 | 1999 | 2019 | ||||||||
|
tyrosine hydroxylase | 0.462 | 0.885 | 1.7E-06 |
|
disease | 0.600 | None | 0.979 | 141 | 3 | 1989 | 2020 | ||||||||
|
glial cell derived neurotrophic factor | 0.434 | 0.885 | 0.20 |
|
disease | 0.400 | None | 0.983 | 117 | 0 | 1993 | 2020 | ||||||||
|
Parkinsonism associated deglycase | 0.535 | 0.808 | 0.75 |
|
disease | 0.600 | None | 0.973 | 110 | 8 | 2003 | 2020 | ||||||||
|
monoamine oxidase B | 0.533 | 0.808 | 1.00 |
|
disease | 0.600 | None | 0.991 | 110 | 1 | 1993 | 2020 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.400 | None | 0.906 | 96 | 6 | 1995 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.922 | 90 | 1 | 1994 | 2020 | ||||||||
|
synuclein beta | 0.619 | 0.577 | 6.8E-02 |
|
disease | 0.100 | None | 0.966 | 89 | 2 | 1999 | 2020 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
disease | 0.100 | None | 0.953 | 85 | 6 | 1984 | 2020 | ||||||||
|
ubiquitin C-terminal hydrolase L1 | 0.482 | 0.885 | 0.99 |
|
disease | 0.100 | None | 0.948 | 77 | 4 | 1999 | 2020 | ||||||||
|
synuclein gamma | 0.550 | 0.615 | 8.5E-04 |
|
disease | 0.100 | None | 0.959 | 74 | 1 | 1999 | 2020 | ||||||||
|
nuclear receptor subfamily 4 group A member 2 | 0.529 | 0.846 | 1.00 |
|
disease | 0.300 | None | 0.973 | 73 | 2 | 1999 | 2019 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.100 | None | 0.983 | 59 | 6 | 2006 | 2020 | ||||||||
|
cytochrome P450 family 2 subfamily D member 6 | 0.437 | 0.885 | 1.1E-25 |
|
disease | 0.400 | None | 0.879 | 58 | 0 | 1992 | 2019 | ||||||||
|
dopamine receptor D2 | 0.436 | 0.846 | 0.75 |
|
disease | 0.600 | None | 0.931 | 58 | 3 | 1995 | 2020 | ||||||||
|
VPS35 retromer complex component | 0.656 | 0.500 | 0.97 |
|
disease | 0.400 | None | 0.931 | 58 | 2 | 2011 | 2019 | ||||||||
|
ATPase cation transporting 13A2 | 0.566 | 0.577 | 9.0E-09 |
|
disease | 0.600 | strong | 0.946 | 56 | 4 | 2007 | 2019 | ||||||||
|
mitochondrial E3 ubiquitin protein ligase 1 | 0.473 | 0.808 | 1.9E-06 |
|
disease | 0.100 | None | 1.000 | 56 | 2 | 2002 | 2019 | ||||||||
|
Cbl proto-oncogene like 2 | 0.476 | 0.808 |
|
disease | 0.100 | None | 1.000 | 54 | 0 | 2002 | 2019 |