| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.964 | 168 | 8 | 1988 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.100 | None | 1.000 | 28 | 7 | 1998 | 2019 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 0.100 | None | 1.000 | 12 | 7 | 2009 | 2019 | ||||||||
|
LIM domain only 1 | 0.623 | 0.538 | 0.64 |
|
disease | 0.100 | None | 1.000 | 15 | 6 | 2011 | 2020 | ||||||||
|
ALK receptor tyrosine kinase | 0.396 | 0.846 | 3.2E-06 |
|
disease | 0.100 | None | 0.951 | 164 | 5 | 2000 | 2020 | ||||||||
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.100 | None | 0.990 | 100 | 5 | 1989 | 2020 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.100 | None | 1.000 | 34 | 4 | 1988 | 2019 | ||||||||
|
Parkinsonism associated deglycase | 0.535 | 0.808 | 0.75 |
|
disease | 0.030 | None | 1.000 | 3 | 4 | 2005 | 2017 | ||||||||
|
lin-28 homolog A | 0.523 | 0.731 | 1.9E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 4 | 2015 | 2020 | ||||||||
|
MYCN proto-oncogene, bHLH transcription factor | 0.454 | 0.808 | 0.89 |
|
disease | 0.100 | None | 0.974 | 836 | 3 | 1984 | 2020 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.100 | None | 0.967 | 60 | 3 | 1998 | 2020 | ||||||||
|
Rho GTPase activating protein 24 | 0.456 | 0.808 | 3.9E-10 |
|
disease | 0.100 | None | 0.931 | 29 | 3 | 1997 | 2015 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.100 | None | 1.000 | 17 | 3 | 1999 | 2017 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.100 | None | 1.000 | 11 | 3 | 2011 | 2018 | ||||||||
|
MYCN opposite strand | 0.700 | 0.462 |
|
disease | 0.080 | None | 0.875 | 8 | 3 | 2009 | 2019 | |||||||||
|
transthyretin | 0.423 | 0.885 | 0.52 |
|
disease | 0.080 | None | 1.000 | 8 | 3 | 2002 | 2014 | ||||||||
|
cancer susceptibility 15 | 0.603 | 0.577 |
|
disease | 0.060 | None | 1.000 | 6 | 3 | 2013 | 2018 | |||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.040 | None | 1.000 | 4 | 3 | 2006 | 2016 | ||||||||
|
solute carrier family 19 member 1 | 0.523 | 0.692 | 6.5E-06 |
|
disease | 0.030 | None | 1.000 | 3 | 3 | 2014 | 2015 | ||||||||
|
ERCC excision repair 5, endonuclease | 0.499 | 0.731 | 2.7E-13 |
|
disease | 0.010 | None | < 0.001 | 1 | 3 | 2016 | 2016 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 3 | 2015 | 2015 | ||||||||
|
tyrosine hydroxylase | 0.462 | 0.885 | 1.7E-06 |
|
disease | 0.100 | None | 0.964 | 56 | 2 | 1989 | 2018 | ||||||||
|
paired like homeobox 2B | 0.565 | 0.731 | 0.94 |
|
disease | 0.100 | None | 0.925 | 53 | 2 | 2004 | 2020 | ||||||||
|
tumor protein p73 | 0.449 | 0.808 | 1.00 |
|
disease | 0.100 | None | 0.933 | 30 | 2 | 1997 | 2015 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.100 | None | 1.000 | 22 | 2 | 1998 | 2019 |