Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 176
Gene Symbol: ACAN
ACAN 		aggrecan 0.528 0.846 1.00
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.100 None 0.962 26 0 2002 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		actin beta 0.325 0.923 0.99
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1 		ADAM metallopeptidase with thrombospondin type 1 motif 1 0.555 0.654 0.72
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2009 2009
Entrez Id: 9508
Gene Symbol: ADAMTS3
ADAMTS3 		ADAM metallopeptidase with thrombospondin type 1 motif 3 0.581 0.808 1.0E-10
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 1.000 4 0 2006 2019
Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4 		ADAM metallopeptidase with thrombospondin type 1 motif 4 0.582 0.692 2.0E-06
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.050 None 1.000 5 0 2006 2019
Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5 		ADAM metallopeptidase with thrombospondin type 1 motif 5 0.597 0.654 8.0E-07
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.040 None 1.000 4 0 2017 2019
Entrez Id: 11173
Gene Symbol: ADAMTS7
ADAMTS7 		ADAM metallopeptidase with thrombospondin type 1 motif 7 0.666 0.577 2.3E-14
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2015 2015
Entrez Id: 57211
Gene Symbol: ADGRG6
ADGRG6 		adhesion G protein-coupled receptor G6 0.666 0.385 6.6E-05
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B 		alcohol dehydrogenase 1B (class I), beta polypeptide 0.502 0.846 9.9E-07
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2007 2007
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1 		activator of HSP90 ATPase activity 1 0.396 0.923 1.00
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.020 None 1.000 2 0 2011 2016
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2 		aminoacyl tRNA synthetase complex interacting multifunctional protein 2 0.393 0.923 8.0E-03
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.020 None 1.000 2 0 2011 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 268
Gene Symbol: AMH
AMH 		anti-Mullerian hormone 0.476 0.846 3.4E-12
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2 		angiopoietin 2 0.410 0.846 0.83
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 55908
Gene Symbol: ANGPTL8
ANGPTL8 		angiopoietin like 8 0.650 0.577 6.9E-12
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2019 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 360
Gene Symbol: AQP3
AQP3 		aquaporin 3 (Gill blood group) 0.546 0.769 0.13
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 367
Gene Symbol: AR
AR 		androgen receptor 0.351 0.846 0.99
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9311
Gene Symbol: ASIC3
ASIC3 		acid sensing ion channel subunit 3 0.663 0.538 3.4E-07
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.030 None 1.000 3 0 2016 2019
Entrez Id: 54829
Gene Symbol: ASPN
ASPN 		asporin 0.636 0.500 1.0E-07
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.030 None 1.000 3 0 2009 2017
Entrez Id: 79058
Gene Symbol: ASPSCR1
ASPSCR1 		ASPSCR1 tether for SLC2A4, UBX domain containing 0.653 0.538 4.4E-12
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A 		ATPase copper transporting alpha 0.494 0.769 1.00
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 578
Gene Symbol: BAK1
BAK1 		BCL2 antagonist/killer 1 0.555 0.769 7.4E-06
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0158266
Disease: Intervertebral Disc Degeneration
Intervertebral Disc Degeneration 		disease 0.010 None 1.000 1 0 2017 2017