Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.490 Biomarker CTD_human

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 Biomarker CTD_human

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.350 Biomarker CTD_human

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.330 Biomarker CTD_human

Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.330 Biomarker CTD_human

Entrez Id: 201163
Gene Symbol: FLCN
FLCN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 6714
Gene Symbol: SRC
SRC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 699
Gene Symbol: BUB1
BUB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 79695
Gene Symbol: GALNT12
GALNT12
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 2033
Gene Symbol: EP300
EP300
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 3791
Gene Symbol: KDR
KDR
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Therapeutic CTD_human (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells. 20346928

2010

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker CTD_human 4-Hydroxy-2(E)-nonenal metabolism differs in Apc(+/+) cells and in Apc(Min/+) cells: it may explain colon cancer promotion by heme iron. 21967605

2011

Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Therapeutic CTD_human 5-Fluorouracil-interferon-alpha 2b adjuvant treatment of Dukes C colorectal cancer. 8026229

1994

Entrez Id: 6820
Gene Symbol: SULT2B1
SULT2B1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human SULT2B1 expression was significantly higher in colorectal tumor tissues than in normal tissues in the Cancer Genome Atlas (TCGA) database (P < 1.0 × 10<sup>-4</sup>). 29766219

2018

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Biomarker CTD_human A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. 16332725

2006

Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Biomarker CTD_human A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. 16332725

2006

Entrez Id: 8667
Gene Symbol: EIF3H
EIF3H
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 18372905

2008

Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 Biomarker CTD_human A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. 17934461

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351

2011

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker CTD_human A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation. 17047490

2006

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. 17450141

2007

Entrez Id: 8842
Gene Symbol: PROM1
PROM1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.330 Biomarker CTD_human Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. 18829568

2008

Entrez Id: 1487
Gene Symbol: CTBP1
CTBP1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Adenomatous polyposis coli control of C-terminal binding protein-1 stability regulates expression of intestinal retinol dehydrogenases. 17028196

2006