Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57016
Gene Symbol: AKR1B10
AKR1B10
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. 17597105

2007

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.340 Biomarker CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778

2011

Entrez Id: 23643
Gene Symbol: LY96
LY96
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778

2011

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778

2011

Entrez Id: 7037
Gene Symbol: TFRC
TFRC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer. 16111806

2006

Entrez Id: 142
Gene Symbol: PARP1
PARP1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells. 27694308

2016

Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Therapeutic CTD_human Anti-EpCAM monoclonal antibody (MAb17-1A) based treatment combined with alpha-interferon, 5-fluorouracil and granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. 15289873

2004

Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Therapeutic CTD_human Anti-EpCAM monoclonal antibody (MAb17-1A) based treatment combined with alpha-interferon, 5-fluorouracil and granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. 15289873

2004

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 Biomarker CTD_human Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations. 21531761

2011

Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice. 27941798

2017

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker CTD_human Aspirin use and survival after diagnosis of colorectal cancer. 19671906

2009

Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 Biomarker CTD_human Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. 20878130

2010

Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population. 20878130

2010

Entrez Id: 811
Gene Symbol: CALR
CALR
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Therapeutic CTD_human Calreticulin exposure dictates the immunogenicity of cancer cell death. 17187072

2007

Entrez Id: 28234
Gene Symbol: SLCO1B3
SLCO1B3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker. 29491222

2018

Entrez Id: 26585
Gene Symbol: GREM1
GREM1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.430 Biomarker CTD_human Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. 18084292

2008

Entrez Id: 6447
Gene Symbol: SCG5
SCG5
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. 18084292

2008

Entrez Id: 10714
Gene Symbol: POLD3
POLD3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker CTD_human Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. 22634755

2012

Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.320 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007

Entrez Id: 11257
Gene Symbol: TP53TG1
TP53TG1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007

Entrez Id: 668
Gene Symbol: FOXL2
FOXL2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007

Entrez Id: 9148
Gene Symbol: NEURL1
NEURL1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007

Entrez Id: 59345
Gene Symbol: GNB4
GNB4
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007

Entrez Id: 2199
Gene Symbol: FBLN2
FBLN2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007

Entrez Id: 26256
Gene Symbol: CABYR
CABYR
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Comparing the DNA hypermethylome with gene mutations in human colorectal cancer. 17892325

2007