Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10533
Gene Symbol: ATG7
ATG7
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Therapeutic RGD Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. 25542083

2015

Entrez Id: 22933
Gene Symbol: SIRT2
SIRT2
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Therapeutic RGD Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas. 23522375

2013

Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 ModifyingMutation RGD In malignant glioma, however, galectin-3 was expressed in both neoplastic astrocytic cells and microglia. 23179497

2013

Entrez Id: 6455
Gene Symbol: SH3GL1
SH3GL1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 ModifyingMutation RGD Autologous antibody to src-homology 3-domain GRB2-like 1 specifically increases in the sera of patients with low-grade gliomas. 23050879

2012

Entrez Id: 858
Gene Symbol: CAV2
CAV2
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Low-frequency ultrasound irradiation increases blood-tumor barrier permeability by transcellular pathway in a rat glioma model. 22528460

2012

Entrez Id: 4288
Gene Symbol: MKI67
MKI67
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Evaluation of biocompatibility and anti-glioma efficacy of doxorubicin and irinotecan drug-eluting bead suspensions in alginate. 22262719

2012

Entrez Id: 857
Gene Symbol: CAV1
CAV1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Low-frequency ultrasound irradiation increases blood-tumor barrier permeability by transcellular pathway in a rat glioma model. 22528460

2012

Entrez Id: 2057
Gene Symbol: EPOR
EPOR
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Targeting the erythropoietin receptor on glioma cells reduces tumour growth. 21749867

2011

Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH)Arg(9)]-BK in a F98 glioma rat model: an MRI study. 20080302

2010

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. 17287256

2007

Entrez Id: 8877
Gene Symbol: SPHK1
SPHK1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Modulation of P-glycoprotein function by sphingosine kinase-1 in brain endothelial cells. 17316399

2007

Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Intracranial stereotaxic cannulation for development of orthotopic glioblastoma allograft in Sprague-Dawley rats and histoimmunopathological characterization of the brain tumor. 17701349

2007

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD pERK, pAkt and pBad: a possible role in cell proliferation and sustained cellular survival during tumorigenesis and tumor progression in ENU induced transplacental glioma rat model. 16944316

2006

Entrez Id: 2147
Gene Symbol: F2
F2
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Therapeutic RGD The role of thrombin in gliomas. 15975137

2005

Entrez Id: 1435
Gene Symbol: CSF1
CSF1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Antiangiogenic drugs synergize with a membrane macrophage colony-stimulating factor-based tumor vaccine to therapeutically treat rats with an established malignant intracranial glioma. 15728459

2005

Entrez Id: 5110
Gene Symbol: PCMT1
PCMT1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Expression and activity of l-isoaspartyl methyltransferase decrease in stage progression of human astrocytic tumors. 15857672

2005

Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Alteration of striatal dopaminergic function induced by glioma development: a microdialysis and immunohistological study in the rat striatum. 14698456

2004

Entrez Id: 8089
Gene Symbol: YEATS4
YEATS4
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor. 11521196

2001

Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Therapeutic RGD Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. 10830965

2000

Entrez Id: 941
Gene Symbol: CD80
CD80
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cells. 10078962

1999

Entrez Id: 3574
Gene Symbol: IL7
IL7
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-gamma, interleukin-7, or B7-1-transfected tumor cells. 10078962

1999

Entrez Id: 374
Gene Symbol: AREG
AREG
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Increased expression of schwannoma-derived growth factor (SDGF) mRNA in rat tumor cells: involvement of SDGF in the growth promotion of rat gliomas. 8621257

1996

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.210 Biomarker RGD Assessment of blood volume, vessel size, and the expression of angiogenic factors in two rat glioma models: a longitudinal in vivo and ex vivo study. 18615861

2008

Entrez Id: 2833
Gene Symbol: CXCR3
CXCR3
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.210 Biomarker RGD Chemokine-directed migration of tumor-inhibitory neural progenitor cells towards an intracranially growing glioma. 16434036

2006

Entrez Id: 63827
Gene Symbol: BCAN
BCAN
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.210 Biomarker RGD A novel membrane-associated glycovariant of BEHAB/brevican is up-regulated during rat brain development and in a rat model of invasive glioma. 12799382

2003