Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 165 11 1990 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 125 2 2005 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 0.982 57 0 2007 2020
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit 0.376 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 26 1 2010 2019
Entrez Id: 2194
Gene Symbol: FASN
FASN
fatty acid synthase 0.474 0.846 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 17 0 2006 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
notch receptor 1 0.369 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 13 0 2009 2018
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
nuclear factor kappa B subunit 1 0.396 0.923 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 12 0 2007 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 10 1 2010 2018
Entrez Id: 182
Gene Symbol: JAG1
JAG1
jagged canonical Notch ligand 1 0.429 0.808 1.00
Malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 0 2009 2019
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
collagen type II alpha 1 chain 0.444 0.846 1.00
Malignant neoplasm of colon and/or rectum
disease 0.080 None 1.000 8 0 2010 2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
DNA methyltransferase 1 0.406 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.080 None 0.875 8 1 2007 2020
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
fms related receptor tyrosine kinase 4 0.457 0.808 1.00
Malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2003 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.060 None 1.000 6 0 2011 2018
Entrez Id: 80312
Gene Symbol: TET1
TET1
tet methylcytosine dioxygenase 1 0.523 0.808 1.00
Malignant neoplasm of colon and/or rectum
disease 0.060 None 1.000 6 0 2015 2019
Entrez Id: 6093
Gene Symbol: ROCK1
ROCK1
Rho associated coiled-coil containing protein kinase 1 0.513 0.731 1.00
Malignant neoplasm of colon and/or rectum
disease 0.050 None 1.000 5 0 2015 2018
Entrez Id: 1434
Gene Symbol: CSE1L
CSE1L
chromosome segregation 1 like 0.521 0.808 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2012 2016
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
SET domain containing 2, histone lysine methyltransferase 0.424 0.846 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2010 2019
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.450 0.885 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2016 2019
Entrez Id: 7150
Gene Symbol: TOP1
TOP1
DNA topoisomerase I 0.542 0.692 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2012 2019
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A
structural maintenance of chromosomes 1A 0.509 0.808 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2015 2019
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
AT-rich interaction domain 1A 0.455 0.846 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2018 2019
Entrez Id: 9112
Gene Symbol: MTA1
MTA1
metastasis associated 1 0.547 0.692 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2003 2016
Entrez Id: 9839
Gene Symbol: ZEB2
ZEB2
zinc finger E-box binding homeobox 2 0.471 0.808 1.00
Malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2011 2019
Entrez Id: 10075
Gene Symbol: HUWE1
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 0.534 0.769 1.00
Malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2005 2019
Entrez Id: 23030
Gene Symbol: KDM4B
KDM4B
lysine demethylase 4B 0.606 0.462 1.00
Malignant neoplasm of colon and/or rectum
disease 0.030 None 1.000 3 0 2014 2018