×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Approximately 50% of colorectal tumors contain K-ras gene mutations, which occur as an early step in carcinogenesis.
15514939 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Recurrent KRAS codon 146 mutations in human colorectal cancer.
16969076 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Impact of Fc{gamma}RIIa-Fc{gamma}RIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan.
19164213 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Dual effect of Kras(D12) knockdown on tumorigenesis: increased immune-mediated tumor clearance and abrogation of tumor malignancy.
16091732 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
APC, K-ras, and p53 gene mutations in colorectal cancer patients: correlation to clinicopathologic features and postoperative surveillance.
15943410 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
High-degree tumor budding and podia-formation in sporadic colorectal carcinomas with K-ras gene mutations.
17707462 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
K-ras mutations and RASSF1A promoter methylation in colorectal cancer.
12032847 2002
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients.
18577988 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
Biomarker
LHGDN
Role of miR-143 targeting KRAS in colorectal tumorigenesis.
19137007 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
18834226 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
Biomarker
LHGDN
Acquisition of anoikis resistance promotes the emergence of oncogenic K-ras mutations in colorectal cancer cells and stimulates their tumorigenicity in vivo.
17710156 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
Biomarker
LHGDN
KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab.
17998284 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
K-ras mutation detection in colorectal cancer using the Pyrosequencing technique.
17629419 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.
16953233 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Highly conserved sequence of exon 15 BRAF gene and KRAS codon 12 mutation among Greek patients with colorectal cancer.
17393356 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practice.
19056857 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
The aim of this work was to study the prevalence of mutations at codons 12, 13 and 61 of the Ki-ras gene in 37 colorectal tumors from Mexican patients and to correlate them with clinical data.
12908779 2003
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.
17130841 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Molecular detection of TP53, Ki-Ras and p16INK4A promoter methylation in plasma of patients with colorectal cancer and its association with prognosis. Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
16760301 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab.
18202412 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
Biomarker
LHGDN
RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A.
18592002 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
PosttranslationalModification
LHGDN
BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status.
15489648 2004
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Peptide nucleic acid clamp PCR: a novel K-ras mutation detection assay for colorectal cancer micrometastases in lymph nodes.
15221969 2004
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection.
19124802 2009
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Colorectal Neoplasms
0.500
GeneticVariation
LHGDN
Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers.
16918136 2006