Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
phenotype | 0.100 | None | 0.962 | 1455 | 23 | 1990 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 0.967 | 483 | 0 | 1997 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
phenotype | 0.400 | None | 0.920 | 364 | 3 | 1994 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
phenotype | 0.100 | None | 0.967 | 360 | 5 | 1986 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
phenotype | 0.100 | None | 0.977 | 347 | 0 | 1996 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 0.982 | 335 | 1 | 2000 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 0.989 | 283 | 0 | 2000 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
phenotype | 0.100 | None | 0.947 | 281 | 1 | 1997 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
phenotype | 0.400 | None | 0.959 | 266 | 3 | 1990 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
phenotype | 0.100 | None | 0.992 | 265 | 1 | 2000 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 0.992 | 260 | 1 | 2000 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 0.992 | 259 | 0 | 2000 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
phenotype | 0.400 | None | 0.971 | 244 | 4 | 1989 | 2020 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 0.991 | 218 | 0 | 1984 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
phenotype | 0.100 | None | 0.976 | 208 | 2 | 1994 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
phenotype | 0.100 | None | 0.985 | 202 | 1 | 2001 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
phenotype | 0.100 | None | 0.964 | 195 | 7 | 1990 | 2020 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
phenotype | 0.100 | None | 0.989 | 174 | 1 | 1992 | 2019 | ||||||||
|
MDM2 proto-oncogene | 0.362 | 0.846 | 1.00 |
|
phenotype | 0.100 | None | 0.971 | 173 | 2 | 1994 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
phenotype | 0.400 | None | 0.924 | 157 | 4 | 2003 | 2020 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
phenotype | 0.100 | None | 0.993 | 152 | 0 | 1995 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
phenotype | 0.100 | None | 0.973 | 146 | 2 | 1997 | 2019 | ||||||||
|
H3 histone pseudogene 10 | 0.350 | 0.846 |
|
phenotype | 0.100 | None | 0.867 | 143 | 0 | 1995 | 2019 | |||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
phenotype | 0.100 | None | 0.993 | 142 | 0 | 1999 | 2019 | |||||||||
|
enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.376 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 0.993 | 135 | 2 | 2004 | 2020 |