Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1489
Gene Symbol: CTF1
CTF1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.200 Biomarker MGD Cardiotrophin-1 is a key regulator of glucose and lipid metabolism. 21803294

2011
Entrez Id: 10116
Gene Symbol: FEM1B
FEM1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.200 Biomarker MGD Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the Fem1b gene. 16024793

2005
Entrez Id: 401
Gene Symbol: PHOX2A
PHOX2A
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.200 Biomarker MGD The lipid phosphatase SHIP2 controls insulin sensitivity. 11343120

2001
Entrez Id: 434
Gene Symbol: ASIP
ASIP
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.200 Biomarker MGD General survey of diabetic features of yellow KK mice. 5468422

1970
Entrez Id: 5584
Gene Symbol: PRKCI
PRKCI
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.200 Biomarker MGD

Entrez Id: 90480
Gene Symbol: GADD45GIP1
GADD45GIP1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.200 Biomarker MGD

Entrez Id: 51167
Gene Symbol: CYB5R4
CYB5R4
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.210 Biomarker MGD Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. 15247412

2004
Entrez Id: 5507
Gene Symbol: PPP1R3C
PPP1R3C
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.210 Biomarker MGD PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance. 12727934

2003
Entrez Id: 4779
Gene Symbol: NFE2L1
NFE2L1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.210 Biomarker MGD

Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.210 Biomarker MGD

Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.230 Biomarker MGD Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice. 9844009

1998
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.230 Biomarker MGD Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. 9771748

1998
Entrez Id: 8567
Gene Symbol: MADD
MADD
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.230 Biomarker MGD

Entrez Id: 389692
Gene Symbol: MAFA
MAFA
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.250 Biomarker MGD MafA is a key regulator of glucose-stimulated insulin secretion. 15923615

2005
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.300 Biomarker MGD Impaired musculoskeletal response to age and exercise in PPARβ(-/-) diabetic mice. 25279796

2014
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.370 Biomarker MGD

Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.520 Biomarker MGD Replacing SNAP-25b with SNAP-25a expression results in metabolic disease. 26195742

2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD Adipocyte Xbp1s overexpression drives uridine production and reduces obesity. 29551634

2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD SHBG-C57BL/ksJ-db/db: A New Mouse Model to Study SHBG Expression and Regulation During Obesity Development. 26441241

2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells. 24332968

2014
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD To determine the role of glucagon action in diet-induced and genetic type 2 diabetes (T2D), we studied high-fat-diet-induced obese (DIO) and leptin receptor-defective (LepR(-/-)) rodents with and without glucagon receptors (GcgRs). 25157166

2014
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD Prostaglandin transporter modulates wound healing in diabetes by regulating prostaglandin-induced angiogenesis. 22609345

2012
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD BTBR Ob/Ob mutant mice model progressive diabetic nephropathy. 20634301

2010
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance. 17095713

2007
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.600 Biomarker MGD Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. 17268472

2007