Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2934
Gene Symbol: GSN
GSN
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Circulating actin-gelsolin complexes following oleic acid-induced lung injury. 2829631

1988
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats. 8952535

1996
Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.600 Biomarker RGD Exudative lung injury is associated with decreased levels of surfactant proteins in a rat model of meconium aspiration. 9374572

1997
Entrez Id: 653509
Gene Symbol: SFTPA1
SFTPA1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.260 Biomarker RGD Exudative lung injury is associated with decreased levels of surfactant proteins in a rat model of meconium aspiration. 9374572

1997
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Hemorrhagic shock induces G-CSF expression in bronchial epithelium. 9374735

1997
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.290 Biomarker RGD Elevated transforming growth factor-alpha levels in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome. 9700116

1998
Entrez Id: 4282
Gene Symbol: MIF
MIF
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Effect of anti-macrophage migration inhibitory factor antibody on lipopolysaccharide-induced pulmonary neutrophil accumulation. 9700137

1998
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.600 Biomarker RGD Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury. 10455887

1999
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.600 Biomarker RGD Ventilator-induced lung injury leads to loss of alveolar and systemic compartmentalization of tumor necrosis factor-alpha. 11126266

2000
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Pulmonary expression of iNOS and HO-1 protein is upregulated in a rat model of prehepatic portal hypertension. 11258566

2000
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Cyclooxygenase inhibitors attenuate bradykinin-induced vasoconstriction in septic isolated rat lungs. 10702448

2000
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Activation of type II alveolar epithelial cells during acute endotoxemia. 11880315

2002
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.220 Biomarker RGD Early changes in lung gene expression due to high tidal volume. 12816737

2003
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.600 Biomarker RGD [Studies on the expression of mRNA of anti- and pro-inflammatory cytokines in acute lung injury induced by lipopolysaccharide in rat]. 15461830

2004
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.250 Biomarker RGD Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. 16286274

2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.240 Biomarker RGD Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. 16286274

2005
Entrez Id: 2878
Gene Symbol: GPX3
GPX3
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD NO2-induced acute and chronic lung injury cause imbalance of glutathione metabolism in type II pneumocytes. 16049373

2005
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock. 16484904

2006
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.300 Biomarker RGD Relationship between pulmonary surfactant protein and lipid peroxidation in lung injury due to paraquat intoxication in rats. 17616020

2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.260 Biomarker RGD Production and effects of alpha-melanocyte-stimulating hormone during acute lung injury. 17304115

2007
Entrez Id: 653509
Gene Symbol: SFTPA1
SFTPA1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.260 Biomarker RGD Relationship between pulmonary surfactant protein and lipid peroxidation in lung injury due to paraquat intoxication in rats. 17616020

2007
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Inhibition of inducible nitric oxide synthase attenuates acute endotoxin-induced lung injury in rats. 17324147

2007
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Production and effects of alpha-melanocyte-stimulating hormone during acute lung injury. 17304115

2007
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation. 17544263

2007
Entrez Id: 719
Gene Symbol: C3AR1
C3AR1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation. 17544263

2007