Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3035
Gene Symbol: HARS1
HARS1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker CTD_mouse Evaluation of anti-nuclear antibodies and kidney pathology in Lewis rats following exposure to Libby amphibole asbestos. 23256773

2014
Entrez Id: 11025
Gene Symbol: LILRB3
LILRB3
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker CTD_mouse Blood gene expression profiling detects silica exposure and toxicity. 21602193

2011
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Protective effects of adenosine A2A receptor agonist in ventilator-induced lung injury in rats. 19487932

2009
Entrez Id: 134
Gene Symbol: ADORA1
ADORA1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Ischaemic and pharmacological preconditionings protect liver via adenosine and redox status following hepatic ischaemia/reperfusion in rats. 18307414

2008
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Production and effects of alpha-melanocyte-stimulating hormone during acute lung injury. 17304115

2007
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation. 17544263

2007
Entrez Id: 719
Gene Symbol: C3AR1
C3AR1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation. 17544263

2007
Entrez Id: 6376
Gene Symbol: CX3CL1
CX3CL1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD [Effect of Shenqi Fuzheng injection on fractalkine expression in lung tissue of rats with lipopolysaccharide-induced acute lung injury]. 17302066

2007
Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Spatial coordination of cell-adhesion molecules and redox cycling of iron in the microvascular inflammatory response to pulmonary injury. 17280489

2007
Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock. 16484904

2006
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Activation of type II alveolar epithelial cells during acute endotoxemia. 11880315

2002
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Cyclooxygenase inhibitors attenuate bradykinin-induced vasoconstriction in septic isolated rat lungs. 10702448

2000
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Hemorrhagic shock induces G-CSF expression in bronchial epithelium. 9374735

1997
Entrez Id: 2934
Gene Symbol: GSN
GSN
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.200 Biomarker RGD Circulating actin-gelsolin complexes following oleic acid-induced lung injury. 2829631

1988
Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Polyphenols from Juglans regia L. (walnut) kernel modulate cigarette smoke extract induced acute inflammation, oxidative stress and lung injury in Wistar rats. 20534640

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC). 20724665

2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Inhibition of Rho kinase by fasudil hydrochloride attenuates lung injury induced by intestinal ischemia and reperfusion. 21056587

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model. 21618001

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Platonin mitigates acute lung injury induced by bilateral lower limb ischemia-reperfusion in rats. 20472255

2011
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD A crucial role of nitric oxide in acute lung injury secondary to the acute necrotizing pancreatitis. 20144956

2010
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. 19515386

2009
Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Zinc aspartate alleviates lung injury induced by intestinal ischemia-reperfusion in rats. 18561952

2009
Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Hyperoxia-induced lung injury is dose dependent in Wistar rats. 19895324

2009
Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.210 Biomarker RGD Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention. 18793622

2008