Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.210 Biomarker RGD A crucial role of nitric oxide in acute lung injury secondary to the acute necrotizing pancreatitis. 20144956

2010

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.300 Biomarker RGD A quantitative study of lung dysfunction following haemorrhagic shock in rats. 20041965

2010

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.200 Biomarker RGD Activation of type II alveolar epithelial cells during acute endotoxemia. 11880315

2002

Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.200 Biomarker RGD Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock. 16484904

2006

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.280 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011

Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.220 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011

Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.210 Biomarker RGD Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. 20709317

2011

Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.240 Biomarker RGD Alpha glucocorticoid receptor expression in different experimental rat models of acute lung injury. 17467318

2008

Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.210 Biomarker RGD Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model. 21618001

2011

Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.220 Biomarker RGD Attenuation of lipopolysaccharide-induced acute lung injury by treatment with IL-10. 19386070

2009

Entrez Id: 11025
Gene Symbol: LILRB3
LILRB3
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.200 Biomarker CTD_mouse Blood gene expression profiling detects silica exposure and toxicity. 21602193

2011

Entrez Id: 2934
Gene Symbol: GSN
GSN
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.200 Biomarker RGD Circulating actin-gelsolin complexes following oleic acid-induced lung injury. 2829631

1988

Entrez Id: 2919
Gene Symbol: CXCL1
CXCL1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.220 Biomarker RGD Cyclooxygenase inhibition in ventilator-induced lung injury. 21048090

2011

Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.200 Biomarker RGD Cyclooxygenase inhibitors attenuate bradykinin-induced vasoconstriction in septic isolated rat lungs. 10702448

2000

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Early administration of propofol protects against endotoxin-induced acute lung injury in rats by inhibiting the TGF-beta1-Smad2 dependent pathway. 19941153

2010

Entrez Id: 1958
Gene Symbol: EGR1
EGR1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.220 Biomarker RGD Early changes in lung gene expression due to high tidal volume. 12816737

2003

Entrez Id: 4282
Gene Symbol: MIF
MIF
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.210 Biomarker RGD Effect of anti-macrophage migration inhibitory factor antibody on lipopolysaccharide-induced pulmonary neutrophil accumulation. 9700137

1998

Entrez Id: 7097
Gene Symbol: TLR2
TLR2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.250 Biomarker RGD Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. 16286274

2005

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.240 Biomarker RGD Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis. 16286274

2005

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.560 Biomarker RGD Effects of an angiotensin-converting enzyme inhibitor on the inflammatory response in in vivo and in vitro models. 19114890

2009

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.290 Biomarker RGD Elevated transforming growth factor-alpha levels in bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome. 9700116

1998

Entrez Id: 3035
Gene Symbol: HARS1
HARS1
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.200 Biomarker CTD_mouse Evaluation of anti-nuclear antibodies and kidney pathology in Lewis rats following exposure to Libby amphibole asbestos. 23256773

2014

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Evidence of a central role for p38 map kinase induction of tumor necrosis factor alpha in pancreatitis-associated pulmonary injury. 10455887

1999

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.210 Biomarker RGD Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats. 8952535

1996

Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.600 Biomarker RGD Exudative lung injury is associated with decreased levels of surfactant proteins in a rat model of meconium aspiration. 9374572

1997