Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7037
Gene Symbol: TFRC
TFRC
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats. 23805238

2013

Entrez Id: 2936
Gene Symbol: GSR
GSR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. 24622831

2014

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. 24275070

2014

Entrez Id: 9927
Gene Symbol: MFN2
MFN2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. 26401075

2015

Entrez Id: 57817
Gene Symbol: HAMP
HAMP
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796

2017

Entrez Id: 7124
Gene Symbol: TNF
TNF
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet. 19034968

2008

Entrez Id: 51548
Gene Symbol: SIRT6
SIRT6
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats. 21373642

2011

Entrez Id: 3030
Gene Symbol: HADHA
HADHA
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis. 24782632

2014

Entrez Id: 3416
Gene Symbol: IDE
IDE
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats. 26576191

2015

Entrez Id: 3643
Gene Symbol: INSR
INSR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet in mice]. 29325294

2017

Entrez Id: 23409
Gene Symbol: SIRT4
SIRT4
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats. 20651844

2010

Entrez Id: 4023
Gene Symbol: LPL
LPL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Thiazolidinedione induces a therapeutic effect on hepatosteatosis by regulating stearoyl-CoA desaturase-1, lipase activity, leptin and resistin. 30214514

2018

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal-copper, high-fructose diet in male rats. 25813056

2015

Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Activation of peroxisome proliferator-activated receptor gamma by rosiglitazone increases sirt6 expression and ameliorates hepatic steatosis in rats. 21373642

2011

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Celecoxib ameliorates non-alcoholic steatohepatitis in type 2 diabetic rats via suppression of the non-canonical Wnt signaling pathway expression. 24404139

2014

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis. 23301938

2013

Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats. 24166662

2013

Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis. 22112382

2012

Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). 25317811

2014

Entrez Id: 4023
Gene Symbol: LPL
LPL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Preventive and therapeutic effects of compound ginkgo extract in rats with nonalcoholic steatohepatitis induced by high-fat, high-fructose diet]. 27978932

2016

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD [Effects of puerarin on expressions of leptin receptor mRNA, phosphorylated Janus kinase 2/phosphorylated signal transducers and activators of transcription 3 proteins in the liver of rats with non-alcoholic fatty liver]. 18782535

2008

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effect of electro-acupuncture on hepatic Toll-like receptor 4 and nuclear factor κB expressions in rats with non-alcoholic fatty liver disease]. 25413054

2014

Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. 24275070

2014

Entrez Id: 5445
Gene Symbol: PON2
PON2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease. 22536512

2012