Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4023
Gene Symbol: LPL
LPL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Thiazolidinedione induces a therapeutic effect on hepatosteatosis by regulating stearoyl-CoA desaturase-1, lipase activity, leptin and resistin. 30214514

2018

Entrez Id: 5264
Gene Symbol: PHYH
PHYH
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics for the investigation of the effect of Hugan Qingzhi on non-alcoholic fatty liver disease in rats. 29031784

2018

Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Enhancement of Adiponectin Ameliorates Nonalcoholic Fatty Liver Disease via Inhibition of FoxO1 in Type I Diabetic Rats. 30186875

2018

Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Curative effect of arjunolic acid from Terminalia arjuna in non-alcoholic fatty liver disease models. 30257410

2018

Entrez Id: 57817
Gene Symbol: HAMP
HAMP
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Hepcidin levels correlate to liver iron content, but not steatohepatitis, in non-alcoholic fatty liver disease. 29871592

2018

Entrez Id: 57817
Gene Symbol: HAMP
HAMP
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. 28051796

2017

Entrez Id: 3643
Gene Symbol: INSR
INSR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet in mice]. 29325294

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Yinchen Linggui Zhugan Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats by Regulating the Nrf2/ARE Signaling Pathway. 28932253

2017

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 ModifyingMutation RGD Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress. 27639593

2017

Entrez Id: 3643
Gene Symbol: INSR
INSR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. 28468951

2017

Entrez Id: 4023
Gene Symbol: LPL
LPL
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Preventive and therapeutic effects of compound ginkgo extract in rats with nonalcoholic steatohepatitis induced by high-fat, high-fructose diet]. 27978932

2016

Entrez Id: 9927
Gene Symbol: MFN2
MFN2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Effects of salvianolic acid B on liver mitochondria of rats with nonalcoholic steatohepatitis. 26401075

2015

Entrez Id: 3416
Gene Symbol: IDE
IDE
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats. 26576191

2015

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Kupffer cell depletion protects against the steatosis, but not the liver damage, induced by marginal-copper, high-fructose diet in male rats. 25813056

2015

Entrez Id: 2936
Gene Symbol: GSR
GSR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. 24622831

2014

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. 24275070

2014

Entrez Id: 3030
Gene Symbol: HADHA
HADHA
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Proteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis. 24782632

2014

Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Celecoxib ameliorates non-alcoholic steatohepatitis in type 2 diabetic rats via suppression of the non-canonical Wnt signaling pathway expression. 24404139

2014

Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). 25317811

2014

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Therapeutic RGD [Effect of electro-acupuncture on hepatic Toll-like receptor 4 and nuclear factor κB expressions in rats with non-alcoholic fatty liver disease]. 25413054

2014

Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 SusceptibilityMutation RGD Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats. 24275070

2014

Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014

Entrez Id: 60
Gene Symbol: ACTB
ACTB
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Protein carbonylation associated to high-fat, high-sucrose diet and its metabolic effects. 25282656

2014

Entrez Id: 27141
Gene Symbol: CIDEB
CIDEB
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
0.200 Biomarker RGD Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets? 25263431

2014