Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 22906
Gene Symbol: TRAK1
TRAK1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 Biomarker LHGDN Identification of TRAK1 (Trafficking protein, kinesin-binding 1) as MGb2-Ag: a novel cancer biomarker. 18986759

2009
Entrez Id: 27122
Gene Symbol: DKK3
DKK3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 PosttranslationalModification LHGDN Moreover, methylation of Dkk-3 was detected in 117 of 173 primary gastric tumors (67.6%) and in 67 of 128 colorectal tumors (52.3%). 19051296

2009
Entrez Id: 10553
Gene Symbol: HTATIP2
HTATIP2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 Biomarker LHGDN There was also a loss or substantial decrease of TIP30 expression in 106 cases of gastric tumors as compared with that in normal gastric mucosa (p<0.05), which was significantly associated with inferior survival duration. 18972434

2009
Entrez Id: 27294
Gene Symbol: DHDH
DHDH
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Overexpression of dihydrodiol dehydrogenase as a prognostic marker in resected gastric cancer patients. 18600452

2009
Entrez Id: 5716
Gene Symbol: PSMD10
PSMD10
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Overexpression of a new gene P28GANK confers multidrug resistance of gastric cancer cells. 19235584

2009
Entrez Id: 1525
Gene Symbol: CXADR
CXADR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 Biomarker LHGDN Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression. 19142187

2009
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Upregulation and secretion of macrophage inhibitory cytokine-1 (MIC-1) in gastric cancers. 19133249

2009
Entrez Id: 2277
Gene Symbol: VEGFD
VEGFD
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Vascular endothelial growth factor-C and -D expression correlates with lymph node micrometastasis in pN0 early gastric cancer. 19117016

2009
Entrez Id: 390
Gene Symbol: RND3
RND3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN RhoE enhances multidrug resistance of gastric cancer cells by suppressing Bax. 19101510

2009
Entrez Id: 3921
Gene Symbol: RPSA
RPSA
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Hypoxia-mediated up-regulation of MGr1-Ag/37LRP in gastric cancers occurs via hypoxia-inducible-factor 1-dependent mechanism and contributes to drug resistance. 19123465

2009
Entrez Id: 7545
Gene Symbol: ZIC1
ZIC1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 PosttranslationalModification LHGDN ZIC1 is downregulated through promoter hypermethylation in gastric cancer. 19135984

2009
Entrez Id: 3304
Gene Symbol: HSPA1B
HSPA1B
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 GeneticVariation LHGDN Protective role of genetic polymorphism of heat shock protein 70-2 for gastric cancer risk. 18478330

2009
Entrez Id: 23213
Gene Symbol: SULF1
SULF1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 PosttranslationalModification LHGDN Promoter hypermethylation correlates with the Hsulf-1 silencing in human breast and gastric cancer. 19006069

2009
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 PosttranslationalModification LHGDN Aberrant silencing of the endocrine peptide gene tachykinin-1 in gastric cancer. 19046942

2009
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 Biomarker LHGDN Expression and significance of HERG protein in gastric cancer. 17938585

2008
Entrez Id: 2273
Gene Symbol: FHL1
FHL1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Clinical significance of loss of Fhl1 expression in human gastric cancer. 18465173

2008
Entrez Id: 5976
Gene Symbol: UPF1
UPF1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. 18427545

2008
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Clinical significance of high mobility group A2 in human gastric cancer and its relationship to let-7 microRNA family. 18413822

2008
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 GeneticVariation LHGDN A new tumor-specific variant of GRP78 as target for antibody-based therapy. 18268478

2008
Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN EGF stimulates uPAR expression and cell invasiveness through ERK, AP-1, and NF-kappaB signaling in human gastric carcinoma cells. 19020743

2008
Entrez Id: 85453
Gene Symbol: TSPYL5
TSPYL5
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 PosttranslationalModification LHGDN In primary gastric tumors, methylation-specific PCR results in 23 of the 36 (63.9%) cases revealed that the hypermethylation at CpG islands of the TSPYL5 was detectable at a high frequency. 18059362

2008
Entrez Id: 5307
Gene Symbol: PITX1
PITX1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 AlteredExpression LHGDN Expression of pituitary homeobox 1 gene in human gastric carcinogenesis and its clinicopathological significance. 18186570

2008
Entrez Id: 23221
Gene Symbol: RHOBTB2
RHOBTB2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 GeneticVariation LHGDN Genetic analysis of the DBC2 gene in gastric cancer. 17906984

2008
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 GeneticVariation LHGDN RANTES-403 polymorphism is associated with reduced risk of gastric cancer in women. 18306985

2008
Entrez Id: 10402
Gene Symbol: ST3GAL6
ST3GAL6
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.010 PosttranslationalModification LHGDN DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer. 18485915

2008