Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.050 Biomarker LHGDN CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells. 16410721

2006

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.050 Biomarker LHGDN DARPP-32 mediates multidrug resistance of gastric cancer through regulation of P-gp and ZNRD1. 18058465

2007

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.050 AlteredExpression LHGDN Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy. 18673531

2008

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.050 GeneticVariation LHGDN Multi-drug resistance 1 polymorphism is associated with reduced risk of gastric cancer in the Japanese population. 17608636

2007

Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 Biomarker LHGDN CIAPIN1 confers multidrug resistance by upregulating the expression of MDR-1 and MRP-1 in gastric cancer cells. 16410721

2006

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.320 GeneticVariation LHGDN The angiotensin II/angiotensin II receptor system correlates with nodal spread in intestinal type gastric cancer. 17548686

2007

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.320 AlteredExpression LHGDN The number of lymph node metastases in gastric cancer correlates with the angiotensin I-converting enzyme gene insertion/deletion polymorphism. 15814629

2005

Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 Biomarker LHGDN The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells. 15300588

2004

Entrez Id: 8745
Gene Symbol: ADAM23
ADAM23
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 PosttranslationalModification LHGDN Infrequent homozygous deletion of ADAM23 was also seen in primary gastric tumors (1/39, 2.6%). 16103878

2005

Entrez Id: 131
Gene Symbol: ADH7
ADH7
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 AlteredExpression LHGDN Alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) activity in the sera of patients with gastric cancer. 18231859

2008

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.020 Biomarker LHGDN Adipokines and ghrelin in gastric cancer cachexia. 18595130

2008

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.020 AlteredExpression LHGDN Plasma adiponectin and gastric cancer. 15701829

2005

Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 Biomarker LHGDN Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2. 17459059

2007

Entrez Id: 79602
Gene Symbol: ADIPOR2
ADIPOR2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 Biomarker LHGDN Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2. 17459059

2007

Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 GeneticVariation LHGDN Role of angiotensinogen gene polymorphism on Helicobacter pylori infection-related gastric cancer risk in Japanese. 17389608

2007

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 Biomarker LHGDN Angiotensin II type 1 receptor expression in human gastric cancer and induces MMP2 and MMP9 expression in MKN-28 cells. 17486447

2008

Entrez Id: 196
Gene Symbol: AHR
AHR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.310 AlteredExpression LHGDN Concurrent expression of aryl hydrocarbon receptor and CYP1A1 but not CYP1A1 MspI polymorphism is correlated with gastric cancers raised in Dalian, China. 16337337

2006

Entrez Id: 57379
Gene Symbol: AICDA
AICDA
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 AlteredExpression LHGDN Activation-induced cytidine deaminase expression in gastric cancer. 18391550

2007

Entrez Id: 9590
Gene Symbol: AKAP12
AKAP12
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 Biomarker LHGDN AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity. 15258566

2004

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.140 AlteredExpression LHGDN NF-kappaB activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis. 18824170

2008

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.140 AlteredExpression LHGDN Reversal of multidrug resistance of gastric cancer cells by downregulation of Akt1 with Akt1 siRNA. 17310852

2006

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.140 Biomarker LHGDN Phospho Akt mediates multidrug resistance of gastric cancer cells through regulation of P-gp, Bcl-2 and Bax. 17725107

2007

Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.010 AlteredExpression LHGDN Expression of angiopoietin 1, 2 and their common receptor Tie2 in human gastric carcinoma: implication for angiogenesis. 16614513

2006

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.030 AlteredExpression LHGDN Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer. 16338068

2006

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.030 Biomarker LHGDN Expression and significance of angiopoietin-2 in gastric cancer. 15112366

2004