×
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Stomach Neoplasms
0.320
AlteredExpression
LHGDN
(4) COX-2, PPARgamma , Bcl-2, and survivin were overexpressed in gastric tumor , but the inhibition of COX-2 activity by Vioxx resulted in a significant reduction in serum and tumor levels of progastrin and gastrin and serum IL-8 and TNF-alpha levels, suggesting that gastrin and proinflammatory cytokines could mediate the up-regulation of COX-2 in gastric cancerogenesis.
14627349 2003
×
Entrez Id: 6867
Gene Symbol: TACC1
TACC1
Stomach Neoplasms
0.010
AlteredExpression
LHGDN
TACC1 -F, a transcript representing the SEREX-identified cDNA clone, was predominantly expressed in brain and gastric tumors to a similar level.12547166 2002
×
Entrez Id: 2520
Gene Symbol: GAST
GAST
Stomach Neoplasms
0.340
AlteredExpression
LHGDN
Gastrin and c-met protein expression were significantly higher in gastric tumor tissue than in IM (P<0.0001).14719064 2004
×
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
Stomach Neoplasms
0.050
GeneticVariation
LHGDN
GSTT1 *0 alone and in combination with GSTM1*0 and GSTP1 variant genotypes is a risk factor for GN in the Indian population.18365908 2008
×
Entrez Id: 51715
Gene Symbol: RAB23
RAB23
Stomach Neoplasms
0.010
Biomarker
LHGDN
RAB23 amplifications in primary gastric tumors were confirmed by both fluorescence in situ hybridization and genomic qPCR, and in two independent patient cohorts from Hong Kong and the United Kingdom RAB23 expression was significantly associated with diffuse-type GC (dGC) compared with intestinal-type GC (iGC).18559507 2008
×
Entrez Id: 11156
Gene Symbol: PTP4A3
PTP4A3
Stomach Neoplasms
0.040
AlteredExpression
LHGDN
PRL-3 phosphatase expression was measured in 137 gastric tumor samples by using the immunohistochemistry method, and the overall survival rate was compared between the patients with high PRL-3 expression (n = 85) and those with moderate or low PRL-3 expression (n = 52).19009246 2009
×
Entrez Id: 6782
Gene Symbol: HSPA13
HSPA13
Stomach Neoplasms
0.010
Biomarker
LHGDN
A genetic variant in the gene encoding the stress70 protein chaperone family member STCH is associated with gastric cancer in the Japanese population.
16087163 2005
×
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
Stomach Neoplasms
0.020
AlteredExpression
LHGDN
A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer.
16035620 2004
×
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
Stomach Neoplasms
0.020
AlteredExpression
LHGDN
A large-scale study of MT1-MMP as a marker for isolated tumor cells in peripheral blood and bone marrow in gastric cancer cases.
18661187 2008
×
Entrez Id: 3309
Gene Symbol: HSPA5
HSPA5
Stomach Neoplasms
0.010
GeneticVariation
LHGDN
A new tumor-specific variant of GRP78 as target for antibody-based therapy.
18268478 2008
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Stomach Neoplasms
0.600
GeneticVariation
LHGDN
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.
18482459 2008
×
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
Stomach Neoplasms
0.050
GeneticVariation
LHGDN
A novel genetic polymorphism of inducible nitric oxide synthase is associated with an increased risk of gastric cancer.
15484300 2004
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Stomach Neoplasms
0.600
GeneticVariation
LHGDN
A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.
16870389 2006
×
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4
Stomach Neoplasms
0.010
GeneticVariation
LHGDN
A novel single nucleotide polymorphism in XRCC4 gene is associated with gastric cancer susceptibility in Taiwan.
17987338 2008
×
Entrez Id: 6794
Gene Symbol: STK11
STK11
Stomach Neoplasms
0.010
GeneticVariation
LHGDN
A novel STK11 germline mutation in two siblings with Peutz-Jeghers syndrome complicated by primary gastric cancer.
15617552 2005
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Stomach Neoplasms
0.500
GeneticVariation
LHGDN
A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer.
17072987 2006
×
Entrez Id: 29108
Gene Symbol: PYCARD
PYCARD
Stomach Neoplasms
0.310
PosttranslationalModification
LHGDN
A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers.
12553049 2003
×
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
Stomach Neoplasms
0.020
GeneticVariation
LHGDN
A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer.
14986114 2004
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Stomach Neoplasms
0.060
GeneticVariation
LHGDN
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
15565457 2005
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Neoplasms
0.700
GeneticVariation
LHGDN
A single nucleotide polymorphism in the transmembrane domain coding region of HER-2 is associated with development and malignant phenotype of gastric cancer.
14520697 2003
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Stomach Neoplasms
0.500
GeneticVariation
LHGDN
A solitary colonic metastasis from gastric cancer detected at an early stage.
18291388 2008
×
Entrez Id: 3756
Gene Symbol: KCNH1
KCNH1
Stomach Neoplasms
0.010
AlteredExpression
LHGDN
Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines.
17873312 2007
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Stomach Neoplasms
0.620
PosttranslationalModification
LHGDN
Aberrant hypermethylation of the FGFR2 gene in human gastric cancer cell lines.
17459342 2007
×
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
Stomach Neoplasms
0.400
PosttranslationalModification
LHGDN
Aberrant methylation within RUNX3 CpG island associated with the nuclear and mitochondrial microsatellite instability in sporadic gastric cancers. Results of a GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study.
17591800 2007
×
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
Stomach Neoplasms
0.010
PosttranslationalModification
LHGDN
Aberrant silencing of the endocrine peptide gene tachykinin-1 in gastric cancer.
19046942 2009