×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.900
Biomarker
MGD
×
Entrez Id:
5663
Gene Symbol:
PSEN1
PSEN1
Alzheimer's Disease
0.700
Biomarker
MGD
×
Entrez Id:
5328
Gene Symbol:
PLAU
PLAU
Alzheimer's Disease
0.680
Biomarker
MGD
×
Entrez Id:
4035
Gene Symbol:
LRP1
LRP1
Alzheimer's Disease
0.300
Biomarker
MGD
×
Entrez Id:
5300
Gene Symbol:
PIN1
PIN1
Alzheimer's Disease
0.300
Biomarker
MGD
×
Entrez Id:
4311
Gene Symbol:
MME
MME
Alzheimer's Disease
0.300
Biomarker
MGD
×
Entrez Id:
857
Gene Symbol:
CAV1
CAV1
Alzheimer's Disease
0.290
Biomarker
MGD
×
Entrez Id:
90865
Gene Symbol:
IL33
IL33
Alzheimer's Disease
0.240
Biomarker
MGD
×
Entrez Id:
23236
Gene Symbol:
PLCB1
PLCB1
Alzheimer's Disease
0.200
Biomarker
MGD
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
"Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD , and the therapeutic effect depends on the integrity of the olfactory nerve pathway.
21585051
2011
×
Entrez Id:
581
Gene Symbol:
BAX
BAX
Alzheimer's Disease
0.520
Therapeutic
RGD
"Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD , and the therapeutic effect depends on the integrity of the olfactory nerve pathway.
21585051
2011
×
Entrez Id:
4137
Gene Symbol:
MAPT
MAPT
Alzheimer's Disease
0.700
Therapeutic
RGD
A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model.
28342971
2017
×
Entrez Id:
3551
Gene Symbol:
IKBKB
IKBKB
Alzheimer's Disease
0.220
Therapeutic
RGD
Acetylpuerarin reduces inflammation and improves memory function in a rat model of Alzheimer's disease induced by Abeta1-42.
24380241
2013
×
Entrez Id:
102
Gene Symbol:
ADAM10
ADAM10
Alzheimer's Disease
0.700
Biomarker
RGD
Acrolein induces Alzheimer's disease-like pathologies in vitro and in vivo.
23296102
2013
×
Entrez Id:
1499
Gene Symbol:
CTNNB1
CTNNB1
Alzheimer's Disease
0.300
Therapeutic
RGD
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils.
12610652
2003
×
Entrez Id:
4311
Gene Symbol:
MME
MME
Alzheimer's Disease
0.300
Therapeutic
RGD
After 28-day administration of NEK and piracetam, the abilities of learning and memory of AD rats in piracetam and low-dose, medium-dose and high-dose NEK groups were significantly improved as compared with the untreated group (P<0.01 or P<0.05); the expression of Abeta(1-42) in hippocampal tissues was decreased (P<0.01 or P<0.05) and the expression of NEP was increased (P<0.01 or P<0.05), especially in the high-dose NEK group.
20141738
2010
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Alzheimer's Disease
0.600
Biomarker
RGD
Akebia Saponin D attenuates amyloid β-induced cognitive deficits and inflammatory response in rats: involvement of Akt/NF-κB pathway.
22963993
2012
×
Entrez Id:
3952
Gene Symbol:
LEP
LEP
Alzheimer's Disease
0.600
Therapeutic
RGD
Amyloid beta lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity.
25296496
2014
×
Entrez Id:
4133
Gene Symbol:
MAP2
MAP2
Alzheimer's Disease
0.300
Biomarker
RGD
An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.
22083255
2012
×
Entrez Id:
4137
Gene Symbol:
MAPT
MAPT
Alzheimer's Disease
0.700
Therapeutic
RGD
Antioxidative and Neuroprotective Effects of Curcumin in an Alzheimer's Disease Rat Model Co-Treated with Intracerebroventricular Streptozotocin and Subcutaneous D-Galactose.
27060945
2016
×
Entrez Id:
596
Gene Symbol:
BCL2
BCL2
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
836
Gene Symbol:
CASP3
CASP3
Alzheimer's Disease
0.600
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
581
Gene Symbol:
BAX
BAX
Alzheimer's Disease
0.520
Therapeutic
RGD
Bajijiasu Ameliorates β-Amyloid-Triggered Endoplasmic Reticulum Stress and Related Pathologies in an Alzheimer's Disease Model.
29587274
2018
×
Entrez Id:
599
Gene Symbol:
BCL2L2
BCL2L2
Alzheimer's Disease
0.210
Therapeutic
RGD
Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats.
20460763
2010
×
Entrez Id:
4803
Gene Symbol:
NGF
NGF
Alzheimer's Disease
0.300
Biomarker
RGD
Brain and serum levels of nerve growth factor in a rat model of Alzheimer's disease .
21368378
2011