Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6382
Gene Symbol: SDC1
SDC1
CUI: C0028754
Disease: Obesity
Obesity
0.210 Biomarker RGD Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance. 11522680

2001

Entrez Id: 1392
Gene Symbol: CRH
CRH
CUI: C0028754
Disease: Obesity
Obesity
0.230 Biomarker RGD Chronic CRF(6-33) infusion suppressed body weight gain and elevated core temperature irrespective of genotype while increasing motor activity in obese rats without altering heart rate or blood pressure. 11564446

2001

Entrez Id: 948
Gene Symbol: CD36
CD36
CUI: C0028754
Disease: Obesity
Obesity
0.300 Biomarker RGD Chronic relocation of the FA transport protein FAT/CD36 to the sarcolemma is observed in obese rodents and humans, and correlates with intramuscular lipid accumulation and insulin resistance. 23743348

2013

Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0028754
Disease: Obesity
Obesity
0.700 Biomarker RGD Creation and preliminary characterization of a leptin knockout rat. 22948215

2012

Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
CUI: C0028754
Disease: Obesity
Obesity
0.200 Biomarker RGD Cyclic nucleotide phosphodiesterase 3 expression in vivo: evidence for tissue-specific expression of phosphodiesterase 3A or 3B mRNA and activity in the aorta and adipose tissue of atherosclerosis-prone insulin-resistant rats. 9648839

1998

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0028754
Disease: Obesity
Obesity
0.260 Biomarker RGD Dietary conjugated linoleic acid preserves pancreatic function and reduces inflammatory markers in obese, insulin-resistant rats. 17161237

2007

Entrez Id: 858
Gene Symbol: CAV2
CAV2
CUI: C0028754
Disease: Obesity
Obesity
0.200 Biomarker RGD Dietary obesity increases NO and inhibits BKCa-mediated, endothelium-dependent dilation in rat cremaster muscle artery: association with caveolins and caveolae. 22492718

2012

Entrez Id: 3929
Gene Symbol: LBP
LBP
CUI: C0028754
Disease: Obesity
Obesity
0.600 Therapeutic RGD Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat. 19917068

2010

Entrez Id: 4852
Gene Symbol: NPY
NPY
CUI: C0028754
Disease: Obesity
Obesity
0.300 Biomarker RGD Difference of NPY and its receptor gene expressions between obesity and obesity-resistant rats in response to high-fat diet. 17447163

2007

Entrez Id: 4886
Gene Symbol: NPY1R
NPY1R
CUI: C0028754
Disease: Obesity
Obesity
0.500 Biomarker RGD Difference of NPY and its receptor gene expressions between obesity and obesity-resistant rats in response to high-fat diet. 17447163

2007

Entrez Id: 4887
Gene Symbol: NPY2R
NPY2R
CUI: C0028754
Disease: Obesity
Obesity
0.300 Biomarker RGD Difference of NPY and its receptor gene expressions between obesity and obesity-resistant rats in response to high-fat diet. 17447163

2007

Entrez Id: 3033
Gene Symbol: HADH
HADH
CUI: C0028754
Disease: Obesity
Obesity
0.510 Biomarker RGD Different forms of obesity as a function of diet composition. 16088331

2005

Entrez Id: 3290
Gene Symbol: HSD11B1
HSD11B1
CUI: C0028754
Disease: Obesity
Obesity
0.600 Biomarker RGD Different responsiveness in body weight and hepatic 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type 1 mrna to 11beta-HSD inhibition by glycyrrhetinic acid treatment in obese and lean zucker rats. 15131764

2004

Entrez Id: 653509
Gene Symbol: SFTPA1
SFTPA1
CUI: C0028754
Disease: Obesity
Obesity
0.200 Biomarker RGD Disaturated phosphatidylcholine (DSPC) in lung tissue and surfactant pellets (large aggregates) and SP-A and SP-B levels in large aggregates were higher in obese than control rats. 15136884

2004

Entrez Id: 6439
Gene Symbol: SFTPB
SFTPB
CUI: C0028754
Disease: Obesity
Obesity
0.200 Biomarker RGD Disaturated phosphatidylcholine (DSPC) in lung tissue and surfactant pellets (large aggregates) and SP-A and SP-B levels in large aggregates were higher in obese than control rats. 15136884

2004

Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity
0.700 Biomarker RGD Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats. 27465994

2016

Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0028754
Disease: Obesity
Obesity
0.600 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0028754
Disease: Obesity
Obesity
0.300 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
CUI: C0028754
Disease: Obesity
Obesity
0.270 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
CUI: C0028754
Disease: Obesity
Obesity
0.230 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 7376
Gene Symbol: NR1H2
NR1H2
CUI: C0028754
Disease: Obesity
Obesity
0.220 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
CUI: C0028754
Disease: Obesity
Obesity
0.200 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 6554
Gene Symbol: SLC10A1
SLC10A1
CUI: C0028754
Disease: Obesity
Obesity
0.200 ModifyingMutation RGD Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. 25612518

2015

Entrez Id: 958
Gene Symbol: CD40
CD40
CUI: C0028754
Disease: Obesity
Obesity
0.520 Therapeutic RGD Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats. 21670556

2011

Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0028754
Disease: Obesity
Obesity
0.220 Biomarker RGD Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin. 16316351

2005