Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 8660
Gene Symbol: IRS2
IRS2 		insulin receptor substrate 2 0.535 0.654 0.99
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.975 0 0 1997 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.953 6 10 1998 2020
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B 		HNF1 homeobox B 0.473 0.808 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.800 None 0.978 5 8 1998 2019
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		uncoupling protein 2 0.493 0.808 1.5E-10
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.857 2 0 1998 2019
Entrez Id: 3651
Gene Symbol: PDX1
PDX1 		pancreatic and duodenal homeobox 1 0.530 0.654 1.8E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.956 2 5 1998 2019
Entrez Id: 4760
Gene Symbol: NEUROD1
NEUROD1 		neuronal differentiation 1 0.543 0.808 0.77
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.800 strong 0.920 4 1 1999 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.950 3 0 1999 2020
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.900 2 0 1999 2019
Entrez Id: 489
Gene Symbol: ATP2A3
ATP2A3 		ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 0.617 0.577 2.2E-09
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.320 None 1.000 1 0 1999 2019
Entrez Id: 2784
Gene Symbol: GNB3
GNB3 		G protein subunit beta 3 0.518 0.808 3.3E-11
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.923 1 0 1999 2018
Entrez Id: 5078
Gene Symbol: PAX4
PAX4 		paired box 4 0.644 0.423 4.2E-04
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 1.000 limited 0.857 1 2 1999 2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		endothelin 1 0.380 0.846 0.46
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 1.000 1 0 1999 2019
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1 		protein tyrosine phosphatase non-receptor type 1 0.523 0.731 0.81
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.500 None 0.961 0 0 1999 2019
Entrez Id: 6462
Gene Symbol: SHBG
SHBG 		sex hormone binding globulin 0.438 0.808 1.3E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.965 1 0 2000 2019
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10 		calpain 10 0.621 0.577 6.9E-13
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.926 1 4 2000 2019
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		peroxisome proliferator activated receptor alpha 0.432 0.885 3.0E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.966 1 0 2000 2020
Entrez Id: 9479
Gene Symbol: MAPK8IP1
MAPK8IP1 		mitogen-activated protein kinase 8 interacting protein 1 0.716 0.462 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.620 None 1.000 1 1 2000 2018
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1 		ectonucleotide pyrophosphatase/phosphodiesterase 1 0.498 0.808 5.0E-08
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 moderate 0.814 0 0 2000 2019
Entrez Id: 208
Gene Symbol: AKT2
AKT2 		AKT serine/threonine kinase 2 0.474 0.769 0.64
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.960 None 1.000 4 1 2001 2018
Entrez Id: 3990
Gene Symbol: LIPC
LIPC 		lipase C, hepatic type 0.585 0.654 3.3E-07
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.680 None 1.000 3 1 2001 2018
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.925 2 0 2001 2020
Entrez Id: 5891
Gene Symbol: MOK
MOK 		MOK protein kinase 0.476 0.769 8.8E-22
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 1.000 1 0 2001 2019
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B 		TNF receptor superfamily member 1B 0.425 0.885 0.50
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.390 None 1.000 1 0 2001 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		superoxide dismutase 1 0.379 0.962 0.18
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.929 1 0 2001 2019
Entrez Id: 56729
Gene Symbol: RETN
RETN 		resistin 0.454 0.808 3.7E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.500 None 0.950 0 0 2001 2020