Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. 10874023

2000

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene. 10223196

1999

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene. 10545420

1999

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human Benzo[b]fluoranthene: tumorigenicity in strain A/J mouse lungs, DNA adducts and mutations in the Ki-ras oncogene. 8761429

1996

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months. 7614698

1995

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human Long-term toxicity studies of ozone in F344/N rats and B6C3F1 mice. 8597069

1995

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human Mutations of the Ki-ras protooncogene in 3-methylcholanthrene and urethan-induced and butylated hydroxytoluene-promoted lung tumors of strain A/J and SWR mice. 7750092

1995

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.700 Biomarker CTD_human K-ras mutations in benzotrichloride-induced lung tumors of A/J mice. 8508514

1993