Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Disruption of leptin signaling contributes to cardiac hypertrophy independently of body weight in mice. 12885755

2003
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Impairment of long-term potentiation and spatial memory in leptin receptor-deficient rodents. 12150780

2002
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice. 12136396

2002
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Homozygosity for a null allele of the carbonic anhydrase II gene (Car2n) does not alter IOP while homozygosity for a mutation in the leptin receptor gene (Leprdb) that causes obesity and diabetes results in increased IOP. 11532192

2001
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Brain-derived neurotrophic factor reduces blood glucose level in obese diabetic mice but not in normal mice. 9299565

1997
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. 8177042

1994
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Description of a new model of genetic obesity: the dbPas mouse. 3882910

1985
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Anti-pancreatic immunity in genetically diabetic mice. 6339122

1983
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Diabetic neuropathy in the mutant mouse [C57BL/ks(db/db)]: a morphometric study. 6991317

1980
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD A new mutation (db3J) at the diabetes locus in strain 129/J mice. I. Physiological and histological characterization. 6993269

1980
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Primary myocardial disease in the diabetic mouse. An ultrastructural study. 431046

1979
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD A reproductive endocrine profile in the diabetes (db) mutant mouse. 378276

1979
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD "Endocrine pancreatic cells of postnatal ""diabetes"" (db) mice in cell culture." 393618

1979
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Studies of diabetic nephropathy in animals and man. 823065

1976
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Studies in the diabetic mutant mouse. VI. Evolution of glomerular lesions and associated proteinuria. 5009970

1972
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
CUI: C0028754
Disease: Obesity
Obesity 		0.700 Biomarker MGD Diabetes, a new mutation in the mouse. 5918576

1966