Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. 22610119

2012

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Resveratrol and prostate cancer: promising role for microRNAs. 21714127

2011

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Regulation of phosphatase homologue of tensin protein expression by bone morphogenetic proteins in prostate epithelial cells. 21456062

2011

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines. 20729295

2010

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines. 20729295

2010

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines. 20729295

2010

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study. 19208208

2009

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. 19396168

2009

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 19011039

2009

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor. 19011039

2009

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision. 19081794

2008

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Effects of manganese superoxide dismutase silencing on androgen receptor function and gene regulation: implications for castration-resistant prostate cancer. 18829485

2008

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Effects of manganese superoxide dismutase silencing on androgen receptor function and gene regulation: implications for castration-resistant prostate cancer. 18829485

2008

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Integrative molecular concept modeling of prostate cancer progression. 17173048

2007

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Cellular changes in prostate cancer cells induced by intermittent androgen suppression. 17141945

2007

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Prostate tumors induced by the deletion of Apc have elevated levels of beta-catenin protein and are highly proliferative. 17363566

2007

Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Integrative molecular concept modeling of prostate cancer progression. 17173048

2007

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells. 17003774

2007

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Cellular changes in prostate cancer cells induced by intermittent androgen suppression. 17141945

2007

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer. 16421604

2006

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells. 16877366

2006

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Synthesis and biological evaluation of a nonsteroidal bromine-76-labeled androgen receptor ligand 3-[76Br]bromo-hydroxyflutamide. 16934689

2006

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Therapeutic CTD_human Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway. 16998812

2006

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Insulin-like growth factor-I promotes migration in human androgen-independent prostate cancer cells via the alphavbeta3 integrin and PI3-K/Akt signaling. 16465378

2006