| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
CF transmembrane conductance regulator | 0.424 | 0.885 | 2.2E-58 |
|
phenotype | 0.500 | None | 1.000 | 32 | 0 | 1995 | 2020 | ||||||||
|
nuclear receptor subfamily 5 group A member 1 | 0.479 | 0.731 | 0.99 |
|
phenotype | 0.450 | None | 0.800 | 5 | 0 | 2010 | 2018 | ||||||||
|
aurora kinase C | 0.736 | 0.308 | 7.8E-02 |
|
phenotype | 0.430 | None | 1.000 | 3 | 0 | 2007 | 2019 | ||||||||
|
follicle stimulating hormone subunit beta | 0.631 | 0.577 | 0.34 |
|
phenotype | 0.420 | None | 1.000 | 2 | 0 | 1979 | 2017 | ||||||||
|
androgen receptor | 0.351 | 0.846 | 0.99 |
|
phenotype | 0.400 | None | 0.918 | 47 | 4 | 1995 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
phenotype | 0.400 | None | 0.872 | 39 | 5 | 2003 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
phenotype | 0.400 | None | 0.929 | 12 | 2 | 2002 | 2019 | ||||||||
|
cytochrome P450 family 1 subfamily A member 1 | 0.436 | 0.846 | 1.1E-17 |
|
phenotype | 0.400 | None | 1.000 | 10 | 2 | 2008 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
phenotype | 0.370 | None | 0.857 | 7 | 1 | 2008 | 2018 | ||||||||
|
DNA polymerase gamma, catalytic subunit | 0.457 | 0.846 | 2.1E-09 |
|
phenotype | 0.370 | None | 0.625 | 7 | 0 | 2004 | 2013 | ||||||||
|
5-methyltetrahydrofolate-homocysteine methyltransferase | 0.482 | 0.808 | 2.4E-12 |
|
phenotype | 0.360 | None | 0.833 | 6 | 1 | 2006 | 2017 | ||||||||
|
5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.502 | 0.808 | 2.2E-14 |
|
phenotype | 0.360 | None | 0.714 | 6 | 1 | 2006 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
phenotype | 0.360 | None | 0.833 | 6 | 4 | 2007 | 2018 | ||||||||
|
aryl hydrocarbon receptor | 0.410 | 0.923 | 1.00 |
|
phenotype | 0.340 | None | 1.000 | 4 | 2 | 2004 | 2019 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
phenotype | 0.330 | None | 0.750 | 3 | 0 | 1996 | 2017 | ||||||||
|
paraoxonase 1 | 0.409 | 0.885 | 9.8E-11 |
|
phenotype | 0.330 | None | 1.000 | 3 | 1 | 2011 | 2014 | ||||||||
|
8-oxoguanine DNA glycosylase | 0.453 | 0.808 | 3.9E-12 |
|
phenotype | 0.320 | None | 1.000 | 2 | 1 | 2013 | 2018 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2014 | 2017 | ||||||||
|
MDM2 proto-oncogene | 0.362 | 0.846 | 1.00 |
|
phenotype | 0.310 | None | 1.000 | 1 | 1 | 2012 | 2012 | ||||||||
|
cytochrome P450 family 17 subfamily A member 1 | 0.462 | 0.769 | 2.6E-04 |
|
phenotype | 0.310 | None | 1.000 | 1 | 1 | 2005 | 2014 | ||||||||
|
armadillo repeat containing 2 | 0.805 | 0.115 | 2.5E-09 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
nanos C2HC-type zinc finger 2 | 0.678 | 0.462 | 5.2E-02 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2012 | 2018 | ||||||||
|
dynein axonemal assembly factor 4 | 0.623 | 0.731 | 9.7E-10 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
phenotype | 0.310 | None | 1.000 | 1 | 1 | 2012 | 2012 | ||||||||
|
polyamine modulated factor 1 binding protein 1 | 0.821 | 0.115 | 9.3E-34 |
|
phenotype | 0.310 | None | 1.000 | 1 | 0 | 2018 | 2018 |