×
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
Parkinsonian Disorders
0.700
Therapeutic
RGD
Human Basic Fibroblast Growth Factor Inhibits Tau Phosphorylation via the PI3K/Akt-GSK3β Signaling Pathway in a 6-Hydroxydopamine-Induced Model of Parkinson's Disease.
27228974 2016
×
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Parkinsonian Disorders
0.700
Biomarker
RGD
Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease.
24969022 2014
×
Entrez Id: 7054
Gene Symbol: TH
TH
Parkinsonian Disorders
0.700
Biomarker
RGD
Decreased RGS9 protein level in the striatum of rodents undergoing MPTP or 6-OHDA neurotoxicity.
20561938 2010
×
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Parkinsonian Disorders
0.600
Biomarker
RGD
Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease.
24969022 2014
×
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Parkinsonian Disorders
0.600
Biomarker
RGD
Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat.
22710069 2012
×
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Parkinsonian Disorders
0.600
Therapeutic
RGD
Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.
22041943 2011
×
Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Parkinsonian Disorders
0.600
Therapeutic
RGD
DJ-1-binding compounds prevent oxidative stress-induced cell death and movement defect in Parkinson's disease model rats.
18373560 2008
×
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
Parkinsonian Disorders
0.530
Biomarker
RGD
Mildronate as a regulator of protein expression in a rat model of Parkinson's disease.
22186119 2011
×
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
Parkinsonian Disorders
0.530
Biomarker
RGD
Signaling of glial cell line-derived neurotrophic factor and its receptor GFRα1 induce Nurr1 and Pitx3 to promote survival of grafted midbrain-derived neural stem cells in a rat model of Parkinson disease.
21865882 2011
×
Entrez Id: 2936
Gene Symbol: GSR
GSR
Parkinsonian Disorders
0.500
Therapeutic
RGD
Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: behavioral, neurochemical and immunohistochemical studies.
20951685 2011
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Parkinsonian Disorders
0.500
Biomarker
RGD
[Effect of Bushen Huoxue Decoction on dopamine D2 receptor in the brain of rats with Parkinson's disease].
22126770 2011
×
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Parkinsonian Disorders
0.400
Biomarker
RGD
Grafts of adult subependymal zone neuronal progenitor cells rescue hemiparkinsonian behavioral decline.
15680936 2005
×
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
Parkinsonian Disorders
0.240
Biomarker
RGD
Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.
21291297 2011
×
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
Parkinsonian Disorders
0.220
Therapeutic
RGD
The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism.
24169105 2014
×
Entrez Id: 1312
Gene Symbol: COMT
COMT
Parkinsonian Disorders
0.220
Biomarker
RGD
Early administration of entacapone prevents levodopa-induced motor fluctuations in hemiparkinsonian rats.
15698633 2005
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Parkinsonian Disorders
0.210
Therapeutic
RGD
Repetitive transcranial magnetic stimulation for treatment of lactacystin-induced Parkinsonian rat model.
28881616 2017
×
Entrez Id: 836
Gene Symbol: CASP3
CASP3
Parkinsonian Disorders
0.210
Therapeutic
RGD
Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease.
27016191 2016
×
Entrez Id: 3313
Gene Symbol: HSPA9
HSPA9
Parkinsonian Disorders
0.210
Biomarker
RGD
Mortalin inhibition in experimental Parkinson's disease.
21542017 2011
×
Entrez Id: 4891
Gene Symbol: SLC11A2
SLC11A2
Parkinsonian Disorders
0.210
Biomarker
RGD
Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent.
20125122 2010
×
Entrez Id: 4891
Gene Symbol: SLC11A2
SLC11A2
Parkinsonian Disorders
0.210
Biomarker
RGD
In addition, we report that a mutation in DMT1 that impairs iron transport protects rodents against parkinsonism -inducing neurotoxins MPTP and 6-hydroxydopamine.
19011085 2008
×
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
Parkinsonian Disorders
0.210
Biomarker
RGD
Different parkinsonism models produce a time-dependent induction of COX-2 in the substantia nigra of rats.
16781689 2006
×
Entrez Id: 5979
Gene Symbol: RET
RET
Parkinsonian Disorders
0.210
Biomarker
RGD
Regulation of c-Ret, GFRalpha1, and GFRalpha2 in the substantia nigra pars compacta in a rat model of Parkinson's disease.
12210101 2002
×
Entrez Id: 842
Gene Symbol: CASP9
CASP9
Parkinsonian Disorders
0.200
Therapeutic
RGD
Pre-administration of BAX-inhibiting peptides decrease the loss of the nigral dopaminergic neurons in rats.
26612350 2016
×
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
Parkinsonian Disorders
0.200
Therapeutic
RGD
β-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62.
25424835 2015
×
Entrez Id: 6469
Gene Symbol: SHH
SHH
Parkinsonian Disorders
0.200
Therapeutic
RGD
Lentivirus-mediated delivery of sonic hedgehog into the striatum stimulates neuroregeneration in a rat model of Parkinson disease.
25030123 2014