Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 260431
Gene Symbol: COPD
COPD
Pulmonary disease, chronic obstructive, severe early-onset 0.456 0.885
Acute exacerbation of chronic obstructive airways disease
phenotype 0.100 None 1.000 25 0 2009 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
Acute exacerbation of chronic obstructive airways disease
phenotype 0.050 None 1.000 5 0 2017 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.324 0.923 4.3E-02
Acute exacerbation of chronic obstructive airways disease
phenotype 0.040 None 1.000 4 0 2017 2019
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
angiotensin I converting enzyme 2 0.477 0.769 1.00
Acute exacerbation of chronic obstructive airways disease
phenotype 0.030 None 1.000 3 0 2017 2018
Entrez Id: 551
Gene Symbol: AVP
AVP
arginine vasopressin 0.437 0.846 7.4E-02
Acute exacerbation of chronic obstructive airways disease
phenotype 0.020 None 1.000 2 0 2017 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
Acute exacerbation of chronic obstructive airways disease
phenotype 0.020 None 1.000 2 0 2016 2020
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
Acute exacerbation of chronic obstructive airways disease
phenotype 0.020 None 1.000 2 0 2016 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
Acute exacerbation of chronic obstructive airways disease
phenotype 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
Acute exacerbation of chronic obstructive airways disease
phenotype 0.020 None 1.000 2 0 2018 2018
Entrez Id: 6036
Gene Symbol: RNASE2
RNASE2
ribonuclease A family member 2 0.621 0.692
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6037
Gene Symbol: RNASE3
RNASE3
ribonuclease A family member 3 0.490 0.808
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
protein tyrosine phosphatase receptor type C 0.435 0.808 1.00
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2020 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 51279
Gene Symbol: C1RL
C1RL
complement C1r subcomponent like 0.839 0.231 3.5E-08
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9516
Gene Symbol: LITAF
LITAF
lipopolysaccharide induced TNF factor 0.650 0.462 3.1E-02
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD
surfactant protein D 0.500 0.846 7.5E-05
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 1 2019 2019
Entrez Id: 944
Gene Symbol: TNFSF8
TNFSF8
TNF superfamily member 8 0.610 0.538 0.76
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2018 2018
Entrez Id: 940
Gene Symbol: CD28
CD28
CD28 molecule 0.436 0.885 0.36
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2020 2020
Entrez Id: 8988
Gene Symbol: HSPB3
HSPB3
heat shock protein family B (small) member 3 0.448 0.769 6.1E-05
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2020 2020
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
fibronectin type III and SPRY domain containing 1 like 0.488 0.808 0.23
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2016 2016
Entrez Id: 834
Gene Symbol: CASP1
CASP1
caspase 1 0.413 0.885 3.5E-05
Acute exacerbation of chronic obstructive airways disease
phenotype 0.010 None 1.000 1 0 2018 2018