| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 1995 | 2003 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 2000 | 2011 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.020 | None | 1.000 | 2 | 1 | 2001 | 2013 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2002 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2010 | 2019 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1998 | 1999 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 1997 | 2012 | ||||||||
|
cholesteryl ester transfer protein | 0.512 | 0.731 | 1.2E-23 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.482 | 0.846 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
euchromatic histone lysine methyltransferase 1 | 0.460 | 0.808 | 1.00 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2020 | 2020 | ||||||||
|
cubilin | 0.587 | 0.769 | 4.6E-42 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2019 | 2019 | ||||||||
|
catalase | 0.359 | 0.962 | 1.6E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 | ||||||||
|
retinoic acid receptor responder 2 | 0.519 | 0.731 | 2.7E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
platelet activating factor receptor | 0.575 | 0.731 | 0.24 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
selenoprotein S | 0.628 | 0.615 | 1.4E-09 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2019 | 2019 | ||||||||
|
dipeptidyl peptidase 4 | 0.420 | 0.808 | 7.3E-09 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2020 | 2020 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2001 | 2001 | ||||||||
|
haptoglobin | 0.412 | 0.885 | 1.7E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
golgin A6 family member A | 0.592 | 0.654 | 1.6E-05 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2020 | 2020 |