Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		kallikrein related peptidase 3 0.443 0.885 4.4E-06
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.935 46 0 2002 2020
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH 		parathyroid hormone like hormone 0.453 0.846 0.81
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 42 0 1997 2019
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		TNF receptor superfamily member 11b 0.422 0.808 0.16
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 31 0 2001 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.933 30 4 2007 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1 		folate hydrolase 1 0.453 0.885 6.2E-09
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.966 29 0 2003 2020
Entrez Id: 8600
Gene Symbol: TNFSF11
TNFSF11 		TNF superfamily member 11 0.453 0.846 4.9E-03
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.964 28 1 2007 2020
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2 		RUNX family transcription factor 2 0.437 0.846 0.95
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 23 0 2005 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.952 21 0 2006 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		estrogen receptor 1 0.324 0.962 1.00
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.947 19 0 2004 2020
Entrez Id: 8792
Gene Symbol: TNFRSF11A
TNFRSF11A 		TNF receptor superfamily member 11a 0.480 0.846 8.8E-03
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 18 3 2008 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 18 0 2017 2019
Entrez Id: 29968
Gene Symbol: PSAT1
PSAT1 		phosphoserine aminotransferase 1 0.478 0.846 1.1E-08
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.941 17 0 2011 2019
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1 		PLAG1 zinc finger 0.493 0.808 1.00
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.941 17 0 2011 2019
Entrez Id: 9520
Gene Symbol: NPEPPS
NPEPPS 		aminopeptidase puromycin sensitive 0.519 0.808 1.00
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.941 17 0 2011 2019
Entrez Id: 5627
Gene Symbol: PROS1
PROS1 		protein S 0.467 0.846 4.7E-04
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 0.941 17 0 2011 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 15 0 2006 2019
Entrez Id: 22943
Gene Symbol: DKK1
DKK1 		dickkopf WNT signaling pathway inhibitor 1 0.439 0.885 0.17
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 14 0 2007 2018
Entrez Id: 367
Gene Symbol: AR
AR 		androgen receptor 0.351 0.846 0.99
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 13 0 1996 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 12 0 2005 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 12 0 2007 2019
Entrez Id: 3589
Gene Symbol: IL11
IL11 		interleukin 11 0.481 0.808 3.2E-04
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 11 0 1998 2019
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12 		C-X-C motif chemokine ligand 12 0.379 0.846 0.12
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 11 0 2006 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 11 0 2014 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 10 0 2010 2018
Entrez Id: 655
Gene Symbol: BMP7
BMP7 		bone morphogenetic protein 7 0.498 0.769 0.13
CUI: C0153690
Disease: Secondary malignant neoplasm of bone
Secondary malignant neoplasm of bone 		disease 0.100 None 1.000 10 0 2003 2018