Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Single nucleotide polymorphisms in the CRH receptor 1 (CRHR1) gene interact with ELS experience to predict depression as well as neuroendocrine and neuronal reactivity. 24931706

2015

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET These data are the first in vivo evidence of a role for chromatin modifications in the regulation of Crhr1 gene expression in the hypothalamus, and may provide novel insight into therapeutic approaches to treat depression. 24867333

2015

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Genetic moderation of child maltreatment effects on depression and internalizing symptoms by serotonin transporter linked polymorphic region (5-HTTLPR), brain-derived neurotrophic factor (BDNF), norepinephrine transporter (NET), and corticotropin releasing hormone receptor 1 (CRHR1) genes in African American children. 25422957

2015

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Participants were assessed prospectively for EA up to age 5 and recent chronic stress and depressive symptoms at age 20 and genotyped for CRHR1 single nucleotide polymorphism rs110402 and 5-HTTLPR. 25422958

2015

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.600 Biomarker PSYGENET Allelic variants of the glucocorticoid receptor (GR) gene contribute significantly to both cortisol levels and to measures of psychosis; corticotropin-releasing hormone receptor 1 variants contribute to measures of depression and psychosis. 24933348

2015