×
Entrez Id:
4088
Gene Symbol:
SMAD3
SMAD3
Osteoarthritis of hip
0.440
Biomarker
HPO
×
Entrez Id:
1311
Gene Symbol:
COMP
COMP
Osteoarthritis of hip
0.440
Biomarker
HPO
×
Entrez Id:
8200
Gene Symbol:
GDF5
GDF5
Osteoarthritis of hip
0.420
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
8200
Gene Symbol:
GDF5
GDF5
Osteoarthritis of hip
0.420
Biomarker
HPO
×
Entrez Id:
8200
Gene Symbol:
GDF5
GDF5
Osteoarthritis of hip
0.420
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
1758
Gene Symbol:
DMP1
DMP1
Osteoarthritis of hip
0.300
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
1758
Gene Symbol:
DMP1
DMP1
Osteoarthritis of hip
0.300
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
2487
Gene Symbol:
FRZB
FRZB
Osteoarthritis of hip
0.140
Biomarker
HPO
×
Entrez Id:
1280
Gene Symbol:
COL2A1
COL2A1
Osteoarthritis of hip
0.130
Biomarker
HPO
×
Entrez Id:
176
Gene Symbol:
ACAN
ACAN
Osteoarthritis of hip
0.110
Biomarker
HPO
×
Entrez Id:
6399
Gene Symbol:
TRAPPC2
TRAPPC2
Osteoarthritis of hip
0.100
Biomarker
HPO
×
Entrez Id:
59341
Gene Symbol:
TRPV4
TRPV4
Osteoarthritis of hip
0.100
Biomarker
HPO
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Osteoarthritis of hip
0.100
Biomarker
HPO
×
Entrez Id:
1186
Gene Symbol:
CLCN7
CLCN7
Osteoarthritis of hip
0.100
Biomarker
HPO
×
Entrez Id:
1297
Gene Symbol:
COL9A1
COL9A1
Osteoarthritis of hip
0.020
GeneticVariation
BEFREE
COL9A1 may therefore be a susceptibility locus for female hip OA .
10788539
2000
×
Entrez Id:
1302
Gene Symbol:
COL11A2
COL11A2
Osteoarthritis of hip
0.010
Biomarker
BEFREE
In addition, there was weak evidence of linkage to HLA/COL11A2 (6p21.3) in female hip OA with a corrected P-value of 0.016.
10788539
2000
×
Entrez Id:
1280
Gene Symbol:
COL2A1
COL2A1
Osteoarthritis of hip
0.130
GeneticVariation
BEFREE
Haplotype analysis showed significant association between a specific haplotype of COL2A1 and hip OA (p = 0.024; OR = 1.30).
12096843
2002
×
Entrez Id:
3553
Gene Symbol:
IL1B
IL1B
Osteoarthritis of hip
0.050
Biomarker
BEFREE
The IL-1 ligand cluster encodes for susceptibility to knee OA but not to hip OA , highlighting the genetic heterogeneity of this common, complex disease.
12115182
2002
×
Entrez Id:
3552
Gene Symbol:
IL1A
IL1A
Osteoarthritis of hip
0.030
Biomarker
BEFREE
The IL-1 ligand cluster encodes for susceptibility to knee OA but not to hip OA , highlighting the genetic heterogeneity of this common, complex disease.
12115182
2002
×
Entrez Id:
4146
Gene Symbol:
MATN1
MATN1
Osteoarthritis of hip
0.010
GeneticVariation
BEFREE
We compared genotype frequencies of the MATN-1 gene (1p35) in patients with OA and controls to determine if there is any association between the MATN-1 genotype and OA .
12175111
2003
×
Entrez Id:
3566
Gene Symbol:
IL4R
IL4R
Osteoarthritis of hip
0.010
GeneticVariation
BEFREE
Our data suggest that functional variants within the IL4R gene predispose to hip OA in Caucasian females.
14745651
2004
×
Entrez Id:
3566
Gene Symbol:
IL4R
IL4R
Osteoarthritis of hip
0.010
GeneticVariation
LHGDN
Our data suggest that functional variants within the IL4R gene predispose to hip OA in Caucasian females.
14745651
2004
×
Entrez Id:
2487
Gene Symbol:
FRZB
FRZB
Osteoarthritis of hip
0.140
GeneticVariation
BEFREE
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.
15210948
2004
×
Entrez Id:
2487
Gene Symbol:
FRZB
FRZB
Osteoarthritis of hip
0.140
GeneticVariation
LHGDN
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.
15210948
2004
×
Entrez Id:
7130
Gene Symbol:
TNFAIP6
TNFAIP6
Osteoarthritis of hip
0.010
GeneticVariation
BEFREE
However, genotyping showed lack of association for a nonsynonymous single-nucleotide polymorphism in tumor necrosis factor alpha-induced protein 6 , whereas a single-nucleotide polymorphism in FRZB resulting in an Arg324Gly substitution at the carboxyl terminus was associated with hip OA in the female probands (P = 0.04).
15210948
2004