Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.440 Biomarker HPO

Entrez Id: 1311
Gene Symbol: COMP
COMP
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.440 Biomarker HPO

Entrez Id: 8200
Gene Symbol: GDF5
GDF5
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.420 Biomarker GENOMICS_ENGLAND

Entrez Id: 8200
Gene Symbol: GDF5
GDF5
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.420 Biomarker HPO

Entrez Id: 8200
Gene Symbol: GDF5
GDF5
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.420 Biomarker GENOMICS_ENGLAND

Entrez Id: 1758
Gene Symbol: DMP1
DMP1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.300 Biomarker GENOMICS_ENGLAND

Entrez Id: 1758
Gene Symbol: DMP1
DMP1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.300 Biomarker GENOMICS_ENGLAND

Entrez Id: 2487
Gene Symbol: FRZB
FRZB
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.140 Biomarker HPO

Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.130 Biomarker HPO

Entrez Id: 176
Gene Symbol: ACAN
ACAN
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.110 Biomarker HPO

Entrez Id: 6399
Gene Symbol: TRAPPC2
TRAPPC2
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.100 Biomarker HPO

Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.100 Biomarker HPO

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.100 Biomarker HPO

Entrez Id: 1186
Gene Symbol: CLCN7
CLCN7
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.100 Biomarker HPO

Entrez Id: 3552
Gene Symbol: IL1A
IL1A
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.030 GeneticVariation BEFREE Hip osteoarthritis susceptibility is associated with IL1B -511(G>A) and IL1 RN (VNTR) genotypic polymorphisms in Croatian Caucasian population. 21671260

2011
Entrez Id: 54829
Gene Symbol: ASPN
ASPN
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.050 GeneticVariation BEFREE Hip osteoarthritis is associated with a genetic polymorphism in the aspartic acid repeat in the N-terminal region of the asporin (<i>ASPN</i>) gene; therefore, the present study aimed to investigate whether the CNV of <i>ASPN</i> is involved in the pathogenesis of AD. 28747338

2017
Entrez Id: 1297
Gene Symbol: COL9A1
COL9A1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.020 GeneticVariation BEFREE COL9A1 may therefore be a susceptibility locus for female hip OA. 10788539

2000
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 GeneticVariation BEFREE Frizzled-related protein variants are risk factors for hip osteoarthritis. 16572458

2006
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 GeneticVariation BEFREE Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women. 17419075

2007
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 GeneticVariation LHGDN Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women. 17419075

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.150 Biomarker BEFREE Transforming growth factor β1 (TGF-β1) and interleukin-6 (IL-6) are two pro-inflammatory cytokines included in pathogenesis of OA, bone remodeling and development of bone and joint tissues. 21353594

2011
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 AlteredExpression BEFREE TWIST1 mRNA expression was elevated and correlated with SMAD3 mRNA levels in the OA cohort during the time-course. 22820497

2012
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.150 Biomarker BEFREE Transforming growth factor-β1 (TGF-beta1) and interleukin-6 (IL-6) are included in pathogenesis of OA, as well as in development of the musculoskeletal system. 25603974

2015
Entrez Id: 50515
Gene Symbol: CHST11
CHST11
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 AlteredExpression BEFREE CHST11 was found to be upregulated in OA versus non-OA cartilage (p < 0.001) and was expressed dynamically during chondrogenesis. 27391021

2016
Entrez Id: 56729
Gene Symbol: RETN
RETN
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip 		0.010 Biomarker BEFREE Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis. 28642544

2017