×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Learning our ABCs: Rad50 directs MRN repair functions via adenylate kinase activity from the conserved ATP binding cassette.
17386254 2007
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Breast cancer susceptibility: current knowledge and implications for genetic counselling.
19092773 2009
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Molecular cloning and characterization of splice variants of human RAD50 gene.
10415333 1999
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Multigene testing of moderate-risk genes: be mindful of the missense.
26787654 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
21441914 2011
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.
24549055 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Evaluation of RAD50 in familial breast cancer predisposition.
16385572 2006
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.
19409520 2009
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID.
20805886 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability.
16474176 2006
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Detection of inherited mutations for hereditary cancer using target enrichment and next generation sequencing.
25151137 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
26822949 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers.
18281469 2008
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Human RAD50 makes a functional DNA-binding complex.
25828805 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.
24093751 2013
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.
27913932 2017
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
25452441 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.
24763289 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Evaluation of RAD50 in familial breast cancer predisposition.
16385572 2006
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mutation screening of Mre11 complex genes: indication of RAD50 involvement in breast and ovarian cancer susceptibility.
14684699 2003
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.
24549055 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks.
21035407 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic.
26023681 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Detection of novel germline mutations for breast cancer in non-BRCA1/2 families.
26094658 2015