×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene.
27913932 2017
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels.
28961279 2017
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Multigene testing of moderate-risk genes: be mindful of the missense.
26787654 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
26822949 2016
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Detection of inherited mutations for hereditary cancer using target enrichment and next generation sequencing.
25151137 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Human RAD50 makes a functional DNA-binding complex.
25828805 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
25452441 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic.
26023681 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Detection of novel germline mutations for breast cancer in non-BRCA1/2 families.
26094658 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic.
26023681 2015
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.
24549055 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.
24763289 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.
24549055 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas.
24240112 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.
24894818 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.
24894818 2014
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.
24093751 2013
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
RAD50 and NBS1 are not likely to be susceptibility genes in Chinese non-BRCA1/2 hereditary breast cancer.
21811815 2012
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
21441914 2011
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID.
20805886 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks.
21035407 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
RAD50 gene mutations are not likely a risk factor for breast cancer in Poland.
20571869 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Some common mutations of RAD50 and NBS1 in western populations do not contribute significantly to Chinese non-BRCA1/2 hereditary breast cancer.
19904603 2010
×
Entrez Id: 10111
Gene Symbol: RAD50
RAD50
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Breast cancer susceptibility: current knowledge and implications for genetic counselling.
19092773 2009