<b>Background:</b> Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low resource countries.
<b>Background:</b> Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low resource countries.
<b>Background:</b> Current immunodiagnostic tests for tuberculosis (TB) are based on the detection of an immune response toward mycobacterial antigens injected into the skin or following an <i>in-vitro</i> simulation in interferon gamma-release assays.
<b>BACKGROUND:</b> Screening tuberculosis (TB) contacts is a priority for TB control; however, it remains inadequate in most regions of China.<b>OBJECTIVE:</b> To investigate the progression of latent TB infection (LTBI) using the interferon-gamma release assay (IGRA) in contacts of active TB patients.<b>DESIGN:</b> This longitudinal prospective observational study included 159 household contacts aged ≥14 years without preventive treatment who were followed up for 6 years to compare their conversion and reversion rates using the T-SPOT<i>
<b>Methods:</b> Peripheral blood mononuclear cells from subjects with latent MTB infection (<i>n</i> = 16) and aTB (<i>n</i> = 39) at baseline, weeks 9, 12, and 26 (end of treatment) were analyzed after intracellular interferon gamma staining and overnight stimulation with tuberculin.
<b>Methods:</b> Screening for TB was performed in children in asylum seeker reception centres by tuberculin skin test (TST) or interferon gamma release assay (IGRA).
<b>Objective:</b> This study aimed to compare the effectiveness of titanium mesh cages (TMCs) with autogenous iliac bone grafts (AIBG) in posterior-only surgery for thoracic and lumbar spinal tuberculosis.<b>Design:</b> Retrospective investigative design.<b>Setting:</b> The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.<b>Participants:</b> A total of 146 patients with thoracic or lumbar tuberculosis.<b>Interventions:</b> All patients underwent a posterior-only approach with either a TMC (86 cases) or AIBG (60 cases).<b>Outcomes measures:</b> Operation duration, intraoperative blood loss, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), visual analogue scale (VAS), and related complications were used to compare the effectiveness and feasibility of the two techniques.
<b>Purpose:</b> To evaluate the diagnostic effect of sequential detection of Adenosine deaminase (ADA) screening and T-SPOT assay on tuberculosis (TB) pleurisy in pleural effusion patients.
<i>Mycobacterium tuberculosis</i>/human immunodeficiency virus (MTB/HIV) coinfection presents a special challenge to the prevention and treatment of tuberculosis and HIV/AIDS.
<i>Mycobacterium tuberculosis</i>/human immunodeficiency virus (MTB/HIV) coinfection presents a special challenge to the prevention and treatment of tuberculosis and HIV/AIDS.
0.37-0.89, P = 0.01) and Americans (AA+AG vs. GG: OR = 0.39, 95% CI = 0.27-0.57, P<0.01), and IL-10-819T/C (C allele vs. T allele: OR = 0.83, 95% CI = 0.72-0.96, P = 0.01) and -592A/C (CC+AC vs. AA: OR = 0.65, 95% CI = 0.49-0.85, P = 0.002) polymorphisms were significantly associated with TB risk in Asians.