Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.800 CausalMutation CLINVAR

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.800 CausalMutation CGI

Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.710 CausalMutation CLINVAR

Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.710 Biomarker CTD_human

Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.710 CausalMutation CGI

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.500 CausalMutation CGI

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.500 CausalMutation CLINVAR

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.440 CausalMutation CGI

Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.400 CausalMutation CGI

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.400 CausalMutation CGI

Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.320 Biomarker CTD_human

Entrez Id: 10461
Gene Symbol: MERTK
MERTK
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.310 GeneticVariation UNIPROT

Entrez Id: 7249
Gene Symbol: TSC2
TSC2
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.310 GenomicAlterations CGI

Entrez Id: 7249
Gene Symbol: TSC2
TSC2
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.310 CausalMutation CGI

Entrez Id: 93627
Gene Symbol: TBCK
TBCK
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.300 GeneticVariation UNIPROT

Entrez Id: 51086
Gene Symbol: TNNI3K
TNNI3K
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.300 GeneticVariation UNIPROT

Entrez Id: 5601
Gene Symbol: MAPK9
MAPK9
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.300 GeneticVariation UNIPROT

Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.070 Biomarker BEFREE These results support the view that stromal interstitial collagenase production may play a key role in assisting invasiveness of squamous cell carcinoma of the head and neck. 1323216

1992
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.200 Biomarker BEFREE There is a definite association between immunohistochemical detection of c-erbB-2 and head and neck squamous cell carcinoma, since almost half of the tumor specimens manifested detectable c-erbB-2 protein. 1363518

1993
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.200 AlteredExpression BEFREE C-erbB-2 expression in squamous cell carcinoma of the head and neck. 1377893

1992
Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.080 AlteredExpression BEFREE Peritumoral injection of human IL-2-activated natural killer cells into nude mice consistently induced regression of xenografts of human squamous cell carcinoma of the head and neck (SCCHN). 1535088

1992
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.100 Biomarker BEFREE The human X-ray repair cross-complementing gene 1 (XRCC1) is highly polymorphic in the cells of human head and neck squamous cell carcinoma lines and in a variety of other human cell lines. 1574572

1992
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.150 AlteredExpression BEFREE We have previously demonstrated that the Ha-ras and the Ki-ras oncogenes are overexpressed in squamous cell carcinoma of the head and neck. 1582509

1992
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.500 AlteredExpression BEFREE Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck. 1624295

1992
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		0.150 Biomarker BEFREE The c-Ha-ras gene was analysed by Southern blot hybridisation in 67 specimens of lymph node metastases and in 25 specimens of primary tumours obtained from 85 untreated patients with head and neck squamous cell carcinoma. 1698442

1990