Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease.
|
15541308 |
2004 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor.
|
16272257 |
2005 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance.
|
16533964 |
2006 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.
|
16321986 |
2006 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
|
29125462 |
2017 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Analysis of LRRK2 functional domains in nondominant Parkinson disease.
|
16247070 |
2005 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations.
|
16157909 |
2005 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.
|
30398148 |
2018 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
LRRK2 G2019S is a common mutation in Spanish patients with late-onset Parkinson's disease.
|
16298482 |
2006 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls.
|
18213618 |
2008 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export.
|
25201882 |
2014 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
LRRK2 gene in Parkinson disease: mutation analysis and case control association study.
|
16157901 |
2005 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.
|
29127255 |
2018 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD.
|
16102999 |
2005 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
|
26824392 |
2016 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Genetic and clinical identification of Parkinson's disease patients with LRRK2 G2019S mutation.
|
15929036 |
2005 |
Entrez Id: |
120892 |
Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations.
|
15726496 |
2005 |