Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043

2018
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_human [Functional analysis of drug metabolizing enzymes using gene knockout animals]. 12875239

2003
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_human Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis. 12668988

2003
Entrez Id: 2875
Gene Symbol: GPT
GPT
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_human Nephrotoxic and hepatotoxic effects of triclosan and chlorhexidine in rats. 145039

1977
Entrez Id: 350
Gene Symbol: APOH
APOH
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_human Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. 16099942

2005
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker CTD_human Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity. 17465707

2007
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.400 Biomarker CTD_human Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.400 Biomarker CTD_human Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.400 Biomarker CTD_human Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. 28043905

2017
Entrez Id: 693177
Gene Symbol: MIR592
MIR592
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 223
Gene Symbol: ALDH9A1
ALDH9A1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015
Entrez Id: 407050
Gene Symbol: MIR93
MIR93
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo. 19783637

2009
Entrez Id: 574030
Gene Symbol: MIR362
MIR362
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 406992
Gene Symbol: MIR210
MIR210
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity. 25527335

2015
Entrez Id: 5053
Gene Symbol: PAH
PAH
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015
Entrez Id: 5591
Gene Symbol: PRKDC
PRKDC
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy. 21224054

2011
Entrez Id: 100302197
Gene Symbol: MIR1306
MIR1306
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 10096
Gene Symbol: ACTR3
ACTR3
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015
Entrez Id: 100302236
Gene Symbol: MIR1260A
MIR1260A
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. 21570397

2011
Entrez Id: 5236
Gene Symbol: PGM1
PGM1
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015
Entrez Id: 102465833
Gene Symbol: MIR4433B
MIR4433B
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017
Entrez Id: 407055
Gene Symbol: MIR99A
MIR99A
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017