Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1642
Gene Symbol: DDB1
DDB1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Natural killer cells mediate severe liver injury in a murine model of halothane hepatitis. 21245496

2011

Entrez Id: 406901
Gene Symbol: MIR107
MIR107
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 136319
Gene Symbol: MTPN
MTPN
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 8976
Gene Symbol: WASL
WASL
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 3274
Gene Symbol: HRH2
HRH2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Histamine at low concentrations aggravates rat liver BRL-3A cell injury induced by hypoxia/reoxygenation through histamine H2 receptor in vitro. 22926047

2013

Entrez Id: 718
Gene Symbol: C3
C3
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. 16099942

2005

Entrez Id: 1990
Gene Symbol: CELA1
CELA1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 6653
Gene Symbol: SORL1
SORL1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866

2016

Entrez Id: 407000
Gene Symbol: MIR218-1
MIR218-1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats. 30125006

2018

Entrez Id: 112574
Gene Symbol: SNX18
SNX18
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Blood gene expression signatures predict exposure levels. 17984051

2007

Entrez Id: 27248
Gene Symbol: ERLEC1
ERLEC1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866

2016

Entrez Id: 112869
Gene Symbol: SGF29
SGF29
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: A role in Kupffer cell activation. 30685357

2019

Entrez Id: 100616376
Gene Symbol: MIR4492
MIR4492
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 2638
Gene Symbol: GC
GC
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. 16099942

2005

Entrez Id: 9002
Gene Symbol: F2RL3
F2RL3
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury. 20974703

2011

Entrez Id: 406919
Gene Symbol: MIR130A
MIR130A
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 407007
Gene Symbol: MIR222
MIR222
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 100616259
Gene Symbol: MIR378I
MIR378I
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Hepatitis C virus structural proteins can exacerbate or ameliorate acetaminophen-induced liver injury in mice. 25743375

2015

Entrez Id: 11315
Gene Symbol: PARK7
PARK7
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 442905
Gene Symbol: MIR337
MIR337
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis. 22363424

2012

Entrez Id: 26061
Gene Symbol: HACL1
HACL1
Chemical and Drug Induced Liver Injury
0.300 Biomarker CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866

2016