×
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR
Neoplasm Invasiveness
0.500
Biomarker
CTD_human
Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells.
22261521 2012
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
AKT signaling is involved in fucoidan-induced inhibition of growth and migration of human bladder cancer cells.
24333868 2014
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways.
23867902 2013
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression.
22503731 2012
×
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Manganese superoxide dismutase induces migration and invasion of tongue squamous cell carcinoma via H2O2-dependent Snail signaling.
22580338 2012
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Metallothionein-2A overexpression increases the expression of matrix metalloproteinase-9 and invasion of breast cancer cells.
21187089 2011
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation.
19617202 2011
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Glioblastoma and endothelial cells cross-talk, mediated by SDF-1, enhances tumour invasion and endothelial proliferation by increasing expression of cathepsins B, S, and MMP-9.
19700239 2010
×
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Resveratrol represses YKL-40 expression in human glioma U87 cells.
21029458 2010
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Neoplasm Invasiveness
0.310
Biomarker
CTD_human
Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
20188714 2010
×
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
Neoplasm Invasiveness
0.310
Therapeutic
CTD_human
Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells.
1318976 1992
×
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Long Noncoding RNA (lncRNA) MIR22HG Suppresses Gastric Cancer Progression through Attenuating NOTCH2 Signaling.
30670679 2019
×
Entrez Id: 100126335
Gene Symbol: MIR543
MIR543
Neoplasm Invasiveness
0.300
Therapeutic
CTD_human
miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7.
30710498 2019
×
Entrez Id: 54822
Gene Symbol: TRPM7
TRPM7
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7.
30710498 2019
×
Entrez Id: 693124
Gene Symbol: MIR532
MIR532
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Downregulation of microRNA-532-5p promotes the proliferation and invasion of bladder cancer cells through promotion of HMGB3/Wnt/β-catenin signaling.
30639441 2019
×
Entrez Id: 406966
Gene Symbol: MIR191
MIR191
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells.
29277653 2018
×
Entrez Id: 100126343
Gene Symbol: MIR874
MIR874
Neoplasm Invasiveness
0.300
Therapeutic
CTD_human
Upregulation of miR-874-3p and miR-874-5p inhibits epithelial ovarian cancer malignancy via SIK2.
30004169 2018
×
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract.
29501572 2018
×
Entrez Id: 92140
Gene Symbol: MTDH
MTDH
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
MicroRNA-1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling.
29315995 2018
×
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract.
29501572 2018
×
Entrez Id: 5970
Gene Symbol: RELA
RELA
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Involvement of HIF-1α-regulated miR-21, acting via the Akt/NF-κB pathway, in malignant transformation of HBE cells induced by cigarette smoke extract.
29501572 2018
×
Entrez Id: 100302203
Gene Symbol: MIR1271
MIR1271
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
MicroRNA-1271 suppresses the proliferation and invasion of colorectal cancer cells by regulating metadherin/Wnt signaling.
29315995 2018
×
Entrez Id: 4751
Gene Symbol: NEK2
NEK2
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Deguelin inhibits epithelial-to-mesenchymal transition and metastasis of human non-small cell lung cancer cells by regulating NIMA-related kinase 2.
28509438 2017
×
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer.
27816970 2017
×
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
Neoplasm Invasiveness
0.300
Biomarker
CTD_human
Estrogen and ERα enhanced β-catenin degradation and suppressed its downstream target genes to block the metastatic function of HA22T hepatocellular carcinoma cells via modulating GSK-3β and β-TrCP expression.
26990689 2017