×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Uterine Carcinosarcoma
0.140
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Uterine Carcinosarcoma
0.140
AlteredExpression
BEFREE
AKT, EGFR, C-ErbB-2 , and C-kit expression in uterine carcinosarcoma .
23896716 2013
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Uterine Carcinosarcoma
0.140
AlteredExpression
BEFREE
Demonstration of HER-2/neu overexpression and amplification in uterine carcinosarcoma may represent the first rationale step for further investigations.
16445668 2006
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Uterine Carcinosarcoma
0.140
AlteredExpression
BEFREE
We describe HER-2/neu overexpression and her-2/neu oncogene amplification in a case of uterine carcinosarcoma occurring in a 46-year-old women who had undergone mastectomy and a 2-year postoperative treatment with tamoxifen for invasive breast cancer.
15901136 2005
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Uterine Carcinosarcoma
0.140
GeneticVariation
BEFREE
The current results suggest absence of ERBB-2 overexpression in uterine leiomyosarcoma, uterine adenosarcoma, and endometrial stromal sarcoma, whereas the ERBB-2 gene might have a biologic role in uterine carcinosarcoma and undifferentiated uterine sarcomas.
15581967 2004
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Carcinosarcoma
0.120
GeneticVariation
BEFREE
In addition to TP53 , other recurrently mutated genes harboring putative driver or loss-of-function mutations included PTEN, FBXW7, FGFR2, KRAS, PIK3CA and CTNNB1, genes known to be involved in UCS .
30194005 2018
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
Uterine Carcinosarcoma
0.120
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Carcinosarcoma
0.120
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
Uterine Carcinosarcoma
0.120
GeneticVariation
BEFREE
Molecular alterations of PIK3CA in uterine carcinosarcoma , clear cell, and serous tumors.
25078343 2014
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
Uterine Carcinosarcoma
0.120
GeneticVariation
BEFREE
The expression of AKT, epithelial growth factor receptor, C-Kit, and C-ErbB-2 were studied by immunohistochemistry and exons 9 and 20 of PIK3CA gene were sequences in a cohort of 37 UCS , including 23 early-stage (I and II) and 14 late-stage (III and IV) tumors.
23896716 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Carcinosarcoma
0.120
Biomarker
BEFREE
DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis.
16810312 2006
×
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Uterine Carcinosarcoma
0.110
Biomarker
BEFREE
Genomic analysis showed that most tumors spontaneously acquired <i>Trp53</i> mutations, pointing to a triad of pathways (p53, PI3K, and Fbxw7 ) as the critical combination underpinning uterine carcinosarcoma , and to Fbxw7 as a key driver of this enigmatic endometrial cancer type.
31772025 2019
×
Entrez Id: 5426
Gene Symbol: POLE
POLE
Uterine Carcinosarcoma
0.110
Biomarker
BEFREE
Tumor Mutational Burden Guides Therapy in a Treatment Refractory <i>POLE -</i>Mutant Uterine Carcinosarcoma .
29386312 2018
×
Entrez Id: 5426
Gene Symbol: POLE
POLE
Uterine Carcinosarcoma
0.110
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Uterine Carcinosarcoma
0.110
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 7307
Gene Symbol: U2AF1
U2AF1
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
Uterine Carcinosarcoma
0.100
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C
Uterine Carcinosarcoma
0.050
Biomarker
BEFREE
This is a secondary analysis of a previous multicenter retrospective study examining 906 women with stage I-IV UCS who underwent primary hysterectomy.
31196490 2019
×
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C
Uterine Carcinosarcoma
0.050
Biomarker
BEFREE
This was a secondary analysis of a prior multicenter retrospective study that examined women with stage I-IV UCS who underwent primary hysterectomy.
29971677 2018
×
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C
Uterine Carcinosarcoma
0.050
Biomarker
BEFREE
This is a secondary analysis of multicenter retrospective study examining women with stages I-IV UCS who underwent primary surgery.
30217299 2018