|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Present study investigated association between VDR gene BsmI A/G (rs1544410), ApaI A/C (rs7975232) and TaqI T/C (rs731236) single nucleotide polymorphisms and PCOS risk in South Indian women.
|
28868946 |
2018 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Classic PCOS phenotype is not associated with deficiency of endogenous vitamin D and VDR gene polymorphisms rs731236 (TaqI), rs7975232 (ApaI), rs1544410 (BsmI), rs10735810 (FokI): a case-control study of lower Silesian women.
|
26422783 |
2015 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Our findings demonstrated that VDR ApaI (rs7975232) and VDR BsmI (rs1544410) polymorphisms are correlated with susceptibility to PCOS in the Asian population and VDR TaqI (rs731236), VDR FokI (rs2228570), VDR Tru9I (rs757343) did not reveal a relationship with the PCOS susceptibility.
|
30764792 |
2019 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil.
|
29669566 |
2018 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Odds ratios (ORs) with 95% confidence interval (CIs) were calculated to assess the association between VDR Fok I C/T (rs10735810), BsmI A/G (rs1544410), ApaI A/C (rs7975232), and TaqI T/C (rs731236) polymorphisms and PCOS risk.
|
30687119 |
2018 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our analysis suggests that VDR polymorphism rs731236 might be associated with breast cancer-specific mortality, and if our findings are confirmed in future bigger studies rs731236 might deserve consideration as a prognostic factor in clinical care of patients with breast cancer.
|
23300018 |
2013 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
No significant univariate associations between the polymorphisms, rs11574010 (Cdx-2A > G), rs10735810 (Fok1T > C), or rs731236 (Taq1C > T) and MS risk were observed.
|
19383647 |
2009 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
An association of two single-nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, Apal (rs7975232) and Taql (rs731236), with multiple sclerosis (MS) has been reported in a Caucasian population.
|
19758194 |
2009 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of this study was to determine whether C to T base substitution within TaqI Vitamin D receptor (VDR) gene (rs731236) in exon 9 was a risk factor among patients with breast cancer.
|
28469103 |
2017 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of the study was to determine whether four VDR gene single nucleotide polymorphisms (SNPs: rs1544410, rs731236, rs10735810 and rs4516035) are associated with breast cancer risk in Polish population.
|
18587672 |
2009 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our analysis suggests that VDR polymorphism rs731236 might be associated with breast cancer-specific mortality, and if our findings are confirmed in future bigger studies rs731236 might deserve consideration as a prognostic factor in clinical care of patients with breast cancer.
|
23300018 |
2013 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, rs731236 TT VDR genotype modulates VDR expression and confers protection against MS in HLA-DRB1*15-positive individuals.
|
21664963 |
2011 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of this study was to determine whether C to T base substitution within TaqI Vitamin D receptor (VDR) gene (rs731236) in exon 9 was a risk factor among patients with breast cancer.
|
28469103 |
2017 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of the study was to determine whether four VDR gene single nucleotide polymorphisms (SNPs: rs1544410, rs731236, rs10735810 and rs4516035) are associated with breast cancer risk in Polish population.
|
18587672 |
2009 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
These results suggest that VDR rs2228570 and rs731236 polymorphisms are not related with the risk for MS, and did not confirm interaction between these VDR SNPs and HLADRB1 in the risk for MS.
|
23840333 |
2013 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
The authors found that TC in rs731236, and TG in KY859868 single-nucleotide polymorphism showed significant distribution differences with an increased risk of breast cancer ( p < 0.05, odds ratio = 3.71, 95% confidence interval: 1.04-13.28 and p < 0.001, odds ratio = 7.05, 95% confidence interval: 2.02-24, respectively) compared with the wild-type TT genotype carriers in both single-nucleotide polymorphisms.
|
29022486 |
2017 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The authors found that TC in rs731236, and TG in KY859868 single-nucleotide polymorphism showed significant distribution differences with an increased risk of breast cancer ( p < 0.05, odds ratio = 3.71, 95% confidence interval: 1.04-13.28 and p < 0.001, odds ratio = 7.05, 95% confidence interval: 2.02-24, respectively) compared with the wild-type TT genotype carriers in both single-nucleotide polymorphisms.
|
29022486 |
2017 |
|
rs731236
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
TaqI (rs731236), BsmI (rs1544410), and ApaI (rs7975232), were studied using PCR-RFLP in 137 patients with lung cancer and 156 controls.
|
19644412 |
2009 |
|
rs731236
|
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
Results Our findings suggest a significant association between rs731236 and prostate cancer risk in Asians and African Americans, but rs1544410 was not associated with prostate cancer under three genetic models.
|
28222630 |
2017 |
|
rs731236
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
TaqI (rs731236), BsmI (rs1544410), and ApaI (rs7975232), were studied using PCR-RFLP in 137 patients with lung cancer and 156 controls.
|
19644412 |
2009 |
|
rs731236
|
|
Gestational Diabetes
|
|
0.030 |
GeneticVariation
|
BEFREE |
Two VDR gene variants rs1544410 (OR = 2.03, 95% CI = 1.17-3.51 for CT versus CC) and rs731236 (OR = 2.42, 95% CI = 1.29-4.55 for GA versus AA) were significantly associated with the risk of GDM.
|
31341914 |
2019 |
|
rs731236
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Epidemiological evidence on the relationships between the vitamin D receptor (VDR) single nucleotide polymorphisms (SNPs) rs731236 (TaqI), rs7975232 (ApaI), rs1544410 (BsmI), and rs2228570 (FokI) and Parkinson's disease (PD) is inconsistent.
|
28216333 |
2017 |
|
rs731236
|
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
We also examined vitamin D related genes, VDR and CYP27B1, and found a significant association of PCa with the TaqI polymorphism (rs731236) in the former.
|
21358824 |
2011 |
|
rs731236
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
We genotyped 100 patients with T1D and 96 controls for the FokI (rs10735810), BsmI (rs1544410), ApaI (rs7975232), and TaqI (rs731236) single nucleotide polymorphisms by polymerase chain reaction and restriction fragment length polymorphism analysis.
|
19734102 |
2009 |
|
rs731236
|
|
Nephrolithiasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The results demonstrated that there was no association found between the three SNPs (rs731236, rs7975232 and rs10735810) in the VDR gene and nephrolithiasis, whether in allele or genotype distribution.
|
29549381 |
2019 |