|
rs1800470
|
|
Rotator cuff syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
We observed that carriers of the rare allele of both studied variants of TGFB1, as well as their G/A (rs1800470/rs1800469) haplotype, were less susceptible to RCT (p < 0.05).
|
31444797 |
2020 |
|
rs1800470
|
|
Glioblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
It seems that polymorphism of T29C (L10P, rs1982073, or rs1800470), which has been studied in various cancers such as breast and colon, creates the significant differences plays an important role in GBM prognosis and treatment.
|
31160907 |
2019 |
|
rs1800470
|
|
Leukemia, Myelocytic, Acute
|
|
0.010 |
GeneticVariation
|
BEFREE |
We aimed to evaluate the multivariate effect of TNF-α rs361525, rs1800750, rs1800629, IL-10 rs1800896, rs1800872, IL-6 rs1800795, TGF-β1 rs1800470, IFN-γ rs2430561 single nucleotide polymorphisms (SNPs) on AML risk, the multivariate effect of SNPs on overall survival (OS) in AML and the association between the investigated SNPs and prognostic factors in AML.
|
31373163 |
2019 |
|
rs1800470
|
|
Glioblastoma Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
It seems that polymorphism of T29C (L10P, rs1982073, or rs1800470), which has been studied in various cancers such as breast and colon, creates the significant differences plays an important role in GBM prognosis and treatment.
|
31160907 |
2019 |
|
rs1800470
|
|
Idiopathic Pulmonary Fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Four common SNPs (rs3737002, rs2296160, rs1800470, and rs35705950) were observed to be statistically associated with increased risk of IPF.
|
29920840 |
2018 |
|
rs1800470
|
|
Pulmonary Fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In subgroup analyses by ethnicity or original disease, no statistically significant association between TGF-β1 rs1800470 polymorphisms and PF was demonstrated.This meta-analysis revealed that TGF-β1 rs1800470 polymorphism was not associated with susceptibility to PF development.
|
30212926 |
2018 |
|
rs1800470
|
|
Wheezing
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found an association between rs1800470 (C allele) and atopic wheezing (odds ratio [OR], 0.60; 95% confidence interval [CI], 0.37-0.95) and markers of allergy (OR, 0.41; 95% CI, 0.22-0.79).
|
28284979 |
2017 |
|
rs1800470
|
|
Inflammatory Bowel Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The c.29T>C polymorphism of the transforming growth factor beta-1 (TGFB1) gene, bone mineral density and the occurrence of low-energy fractures in patients with inflammatory bowel disease.
|
28993955 |
2017 |
|
rs1800470
|
|
Erythema Multiforme
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study is to analyze the relationship between functional polymorphisms in the genes encoding vascular endothelial growth factor A (VEGF-A; rs699947) and transforming growth factor beta 1 (TGF-<i>β</i>1; rs1800470) and target lesion revascularization (TLR) risk.
|
28811677 |
2017 |
|
rs1800470
|
|
Complete atrioventricular block
|
|
0.010 |
GeneticVariation
|
BEFREE |
We examined whether three putative polymorphisms in TGFβ1[-509 C/T (rs1800469), +869 C/T (rs1800470), and +11929 C/T (rs1800472)]are associated with CHB infection in a South-Eastern Iranian population.
|
28700046 |
2017 |
|
rs1800470
|
|
Graft-vs-Host Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that donors or recipients with TGF-β1 rs1800469 polymorphism and donors with TGF-β1 rs1800470 polymorphism might be associated with reduced GVHD risk.
|
26544732 |
2016 |
|
rs1800470
|
|
Deficiency of butyryl-CoA dehydrogenase
|
|
0.010 |
GeneticVariation
|
BEFREE |
The polymorphisms rs1800470, rs2285094 and rs6999447 of the TGFB1, PDGFB and VEGF-A genes, respectively, are associated with LLL in patients with SCAD treated by PCI with a metal stent implantation.
|
26930482 |
2016 |
|
rs1800470
|
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
TGF-β1 T29C gene polymorphism may be associated with severity of CAD in male patients.
|
27234600 |
2016 |
|
rs1800470
|
|
Werner Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
Three single nucleotide polymorphisms in transforming growth factor β-1, rs1800470; thrombospondin, type 1, domain-containing 7A, rs12673692; and formiminotransferase N-terminal subdomain-containing gene, rs7605378, showed a significant association with vertebral fracture prevalence, whereas five (α-l-iduronidase, rs3755955; C7orf58, rs190543052; homeobox C4, rs75256744; G patch domain-containing gene 1, rs2287679; and Werner syndrome, rs2230009) were significantly associated with femoral fracture.
|
27018284 |
2016 |
|
rs1800470
|
|
Brain Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Odds ratios and their corresponding 95% confidence intervals were used to assess the influence of TGFB1 rs4803455, rs1800469, and rs1800470 on metastatic brain tumors.
|
25966122 |
2015 |
|
rs1800470
|
|
Polycystic Ovary Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, for rs11466313 deletion/AGG, rs2217130C/T, rs1800469C/T and rs1800470C/T, no significant association with PCOS risk was observed.
|
25594618 |
2015 |
|
rs1800470
|
|
Hashimoto Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was no notable risk for HT afflicted by Leu10Pro (c.869T>C) polymorphism of TGFβ1 gene.
|
26218277 |
2015 |
|
rs1800470
|
|
Carcinoma of bladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that c.29C>T substitution increased the risk of bladder cancer significantly and recessive model of analysis was the best fitted model (p=0.004; OR=1.72 95% CI 1.18-2.50).
|
26048435 |
2015 |
|
rs1800470
|
|
Chronic kidney disease stage 5
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results conclude that TGF-β1 (rs1800470) may increase the risk of both ESRD and T2D in both populations, but TGF-β1 (rs1800469) provided risk for only ESRD in the population of Jammu and Kashmir.
|
25871499 |
2015 |
|
rs1800470
|
|
Severe periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequency of TGF-β1 SNP (29C > T) risk genotype (TT genotype) in severe periodontitis (34%, n = 11) was significantly higher than in non-severe periodontitis (0%, n = 0) (p = 0.04).
|
25119712 |
2015 |
|
rs1800470
|
|
Bladder Neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that c.29C>T substitution increased the risk of bladder cancer significantly and recessive model of analysis was the best fitted model (p=0.004; OR=1.72 95% CI 1.18-2.50).
|
26048435 |
2015 |
|
rs1800470
|
|
Malignant neoplasm of urinary bladder
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that c.29C>T substitution increased the risk of bladder cancer significantly and recessive model of analysis was the best fitted model (p=0.004; OR=1.72 95% CI 1.18-2.50).
|
26048435 |
2015 |
|
rs1800470
|
|
Metastatic malignant neoplasm to brain
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, no significant association between polymorphisms rs4803455 and rs1800470 and the risk of developing brain metastasis were observed.
|
25966122 |
2015 |
|
rs1800470
|
|
Periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
To investigate the potential association of TGF-β1 -509C/T (rs1800469), +869T/C (rs1800470), and +915G/C (rs1800471) polymorphisms with susceptibility to periodontitis.
|
25385297 |
2015 |
|
rs1800470
|
|
Osteoarthritis of the hand
|
|
0.010 |
GeneticVariation
|
BEFREE |
Of the SNPs, rs716508 in A2BP1 was associated with ROA (OR = 0.7, 95% CI 0.5-0.9) and rs1800470 in TGFB1 with symptomatic DIP OA (1.8, 1.2-2.9).
|
24825461 |
2014 |