|
rs1004819
|
|
Takayasu Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, a trend for IL12A rs582054 and IL23R rs1004819 in association with the TA phenotype was detected.
|
26987707 |
2016 |
|
rs103294
|
|
Takayasu Arteritis
|
T |
0.700 |
GeneticVariation
|
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs104895476
|
|
Takayasu Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
A case of infantile Takayasu arteritis with a p.D382E NOD2 mutation: an unusual phenotype of Blau syndrome/early-onset sarcoidosis?
|
22821420 |
2013 |
|
rs10919543
|
|
Takayasu Arteritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
Among the four SNPs, rs10919543 was found to be significantly associated with TA in the studied population.
|
26996483 |
2016 |
|
rs10919543
|
|
Takayasu Arteritis
|
G |
0.720 |
GeneticVariation
|
GWASCAT |
In addition, we identified and confirmed a genetic association between Takayasu arteritis and the FCGR2A/FCGR3A locus on chromosome 1 (rs10919543, OR = 1.81, p = 5.89 × 10(-12)).
|
23830517 |
2013 |
|
rs10919543
|
|
Takayasu Arteritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
In addition, we identified and confirmed a genetic association between Takayasu arteritis and the FCGR2A/FCGR3A locus on chromosome 1 (rs10919543, OR = 1.81, p = 5.89 × 10(-12)).
|
23830517 |
2013 |
|
rs10921544
|
|
Takayasu Arteritis
|
T |
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs113452171
|
|
Takayasu Arteritis
|
T |
0.700 |
GeneticVariation
|
GWASCAT |
Identification of multiple genetic susceptibility loci in Takayasu arteritis.
|
23830517 |
2013 |
|
rs114202986
|
|
Takayasu Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, rs3763288 and rs114202986 in MICA were negatively related to TA either as a whole or in any clinical features.
|
28261975 |
2018 |
|
rs11666543
|
|
Takayasu Arteritis
|
|
0.710 |
GeneticVariation
|
BEFREE |
We identified genetic susceptibility loci for Takayasu arteritis with a genome-wide level of significance in IL6 (rs2069837) (odds ratio [OR] 2.07, P = 6.70 × 10(-9)), RPS9/LILRB3 (rs11666543) (OR 1.65, P = 2.34 × 10(-8)), and an intergenic locus on chromosome 21q22 (rs2836878) (OR 1.79, P = 3.62 × 10(-10)).
|
25604533 |
2015 |
|
rs11666543
|
|
Takayasu Arteritis
|
|
0.710 |
GeneticVariation
|
GWASCAT |
We identified genetic susceptibility loci for Takayasu arteritis with a genome-wide level of significance in IL6 (rs2069837) (odds ratio [OR] 2.07, P = 6.70 × 10(-9)), RPS9/LILRB3 (rs11666543) (OR 1.65, P = 2.34 × 10(-8)), and an intergenic locus on chromosome 21q22 (rs2836878) (OR 1.79, P = 3.62 × 10(-10)).
|
25604533 |
2015 |
|
rs117298325
|
|
Takayasu Arteritis
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs12047961
|
|
Takayasu Arteritis
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs1205
|
|
Takayasu Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
T allele of rs1205 in CRP gene was less frequent in TA.
|
29024426 |
2018 |
|
rs12111032
|
|
Takayasu Arteritis
|
G |
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs12321966
|
|
Takayasu Arteritis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs12524487
|
|
Takayasu Arteritis
|
T |
0.720 |
GeneticVariation
|
GWASCAT |
Identification of multiple genetic susceptibility loci in Takayasu arteritis.
|
23830517 |
2013 |
|
rs12524487
|
|
Takayasu Arteritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
Four single nucleotide polymorphisms (SNPs) those locate in the IL12B region (rs56167332), the MLX region (rs665268), the FCGR2A/FCGR3A locus (rs10919543), and the HLA-B/MICA locus (rs12524487), associated with TA in different population, were genotyped in 123 Chinese TA patients and 147 healthy controls from January 2013 to August 2014.
|
26996483 |
2016 |
|
rs12524487
|
|
Takayasu Arteritis
|
T |
0.720 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs12524487
|
|
Takayasu Arteritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
Our findings indicated that rs12524487 in HLA-B/MICA was a genetic risk factor for TA in a Chinese Han population and rs9366782 in this region was associated with ischemic brain disease in TA but not TA susceptibility.
|
28261975 |
2018 |
|
rs12608210
|
|
Takayasu Arteritis
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs1264457
|
|
Takayasu Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
sHLA-E level is useful as a biomarker of disease activity and course in TA patients. rs1264457 polymorphism is neither associated with susceptibility nor did it influence sHLA-E levels in TA.
|
28425192 |
2018 |
|
rs12980600
|
|
Takayasu Arteritis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs1383258
|
|
Takayasu Arteritis
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study.
|
25604533 |
2015 |
|
rs17133698
|
|
Takayasu Arteritis
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |