Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12524487
rs12524487
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		T 0.720 GeneticVariation GWASCAT Identification of multiple genetic susceptibility loci in Takayasu arteritis. 23830517

2013
dbSNP: rs12524487
rs12524487
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.720 GeneticVariation BEFREE Four single nucleotide polymorphisms (SNPs) those locate in the IL12B region (rs56167332), the MLX region (rs665268), the FCGR2A/FCGR3A locus (rs10919543), and the HLA-B/MICA locus (rs12524487), associated with TA in different population, were genotyped in 123 Chinese TA patients and 147 healthy controls from January 2013 to August 2014. 26996483

2016
dbSNP: rs12524487
rs12524487
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		T 0.720 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs12524487
rs12524487
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.720 GeneticVariation BEFREE Our findings indicated that rs12524487 in HLA-B/MICA was a genetic risk factor for TA in a Chinese Han population and rs9366782 in this region was associated with ischemic brain disease in TA but not TA susceptibility. 28261975

2018
dbSNP: rs10919543
rs10919543
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.720 GeneticVariation BEFREE Among the four SNPs, rs10919543 was found to be significantly associated with TA in the studied population. 26996483

2016
dbSNP: rs10919543
rs10919543
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		G 0.720 GeneticVariation GWASCAT In addition, we identified and confirmed a genetic association between Takayasu arteritis and the FCGR2A/FCGR3A locus on chromosome 1 (rs10919543, OR = 1.81, p = 5.89 × 10(-12)). 23830517

2013
dbSNP: rs10919543
rs10919543
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.720 GeneticVariation BEFREE In addition, we identified and confirmed a genetic association between Takayasu arteritis and the FCGR2A/FCGR3A locus on chromosome 1 (rs10919543, OR = 1.81, p = 5.89 × 10(-12)). 23830517

2013
dbSNP: rs2099684
rs2099684
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.710 GeneticVariation BEFREE The allele and genotype distributions for the other polymorphisms were not significantly associated with TA among the Han Chinese patients.The SNP rs2099684 in FCGR2A/FCGR3A can be considered a genetic risk factor for TA in the Chinese Han population. 27769046

2017
dbSNP: rs2099684
rs2099684
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		C 0.710 GeneticVariation GWASCAT Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. 30498034

2018
dbSNP: rs9380141
rs9380141
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		C 0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs9271539
rs9271539
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs9266745
rs9266745
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		G 0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs7843437
rs7843437
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs7603494
rs7603494
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs4817988
rs4817988
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		G 0.700 GeneticVariation GWASCAT Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. 30498034

2018
dbSNP: rs4817984
rs4817984
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs4463283
rs4463283
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		A 0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs3869115
rs3869115
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		C 0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs17133698
rs17133698
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		C 0.700 GeneticVariation GWASCAT Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. 30498034

2018
dbSNP: rs12608210
rs12608210
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		A 0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs12321966
rs12321966
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs10921544
rs10921544
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		T 0.700 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
dbSNP: rs103294
rs103294
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		T 0.700 GeneticVariation GWASCAT Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. 30498034

2018
dbSNP: rs6871626
rs6871626
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.050 GeneticVariation BEFREE A previous study revealed the association between susceptibility to Takayasu arteritis (TAK) and a single nucleotide polymorphism (SNP) rs6871626 located in IL12B, which encodes interleukin (IL)-12p40, a common component of IL-12p70 and IL-23. 28874185

2017
dbSNP: rs6871626
rs6871626
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.050 GeneticVariation BEFREE Thus, our study points to potential diagnostic use of SNP rs6871626 for predicting disease severity of TAK, with the goal of genotyping-oriented therapy in the near future. 25783557

2016